Evidence map›Paper›PMID 37556668›Full record

ArticleRevista de saude publica2023

Accuracy of yellow fever case definition of epidemiologic surveillance, São Paulo, 2018.

Ana Freitas Ribeiro, Roberta Figueiredo Cavalin, Aparecida Mei Mingrone Klimas, Ricardo Manfredo, Luciana Marques Sansão Borges

Abstract read
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Article in Revista de saude publica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Ana Freitas RibeiroSecretaria de Estado da Saúde de São Paulo. Instituto de Infectologia Emílio Ribas. São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0001-9111-4510
Roberta Figueiredo CavalinSecretaria de Estado da Saúde de São Paulo. Instituto de Infectologia Emílio Ribas. São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0001-6929-9862
Aparecida Mei Mingrone KlimasSecretaria de Estado da Saúde de São Paulo. Instituto de Infectologia Emílio Ribas. São Paulo, SP, Brasil.ORCID http://orcid.org/0009-0007-6929-4202
Ricardo ManfredoSecretaria de Estado da Saúde de São Paulo. Instituto de Infectologia Emílio Ribas. São Paulo, SP, Brasil.ORCID http://orcid.org/0009-0004-2593-8959
Luciana Marques Sansão BorgesSecretaria de Estado da Saúde de São Paulo. Instituto de Infectologia Emílio Ribas. São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0002-6082-1172

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the accuracy of yellow fever (YF) suspected case definitions from the Brazilian Ministry of Health (BMH) and World Health Organization (WHO), as well as propose and evaluate new definitions of suspected cases, considering confirmed and discarded cases.

methodsThe retrospective study was conducted at the Instituto de Infectologia Emílio Ribas (IIER), using the Epidemiologic Surveillance Form of YF cases. From the confirmed and discarded cases of YF, a logistic regression model was developed. The independent variables were used in a proposed definition of a suspected case of YF and its accuracy was evaluated.

resultsIn total, 113 YF suspect cases were reported, with 78 confirmed (69.0%). The definitions by BMH and WHO presented low sensitivity, 59% and 53.8%, and reduced accuracy, 53.1% and 47.8%, respectively. Predictive factors for YF were thrombocytopenia, leukopenia, and elevation of transaminases greater than twice normal. The definition including individual with acute onset of fever, followed by elevation of ALT or AST greater than twice the reference value AND leukopenia OR thrombocytopenia presented high sensitivity (88.3%), specificity (62.9%), and the best accuracy (80.4%), as proposed in the model.

conclusionThe YF suspected case definitions of the BMH and the WHO have low sensitivity. The inclusion of nonspecific laboratory tests increases the accuracy of YF definition.

Indexed as

Yellow FeverBrazilHumansRetrospective Studies

Identifiers

PMID37556668
PMCPMC10355313

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