Evidence map›Paper›PMID 37556501›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Reactive oxygen species are regulated by immune deficiency and Toll pathways in determining the host specificity of honeybee gut bacteria.

Lizhen Guo, Junbo Tang, Min Tang, Shiqi Luo, Xin Zhou

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
15.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 55 citations in OpenAlex.

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  13. Linking the production of reactive oxygen species to the expression of antimicrobial peptides through aquaporin in an arthropod.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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  19. Infection and immunity · 2025
    Review
  20. Host Specificity ofInsects · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lizhen GuoDepartment of Entomology, College of Plant Protection, China Agricultural University, Beijing 100083, People's Republic of China.
Junbo TangDepartment of Entomology, College of Plant Protection, China Agricultural University, Beijing 100083, People's Republic of China.
Min TangDepartment of Entomology, College of Plant Protection, China Agricultural University, Beijing 100083, People's Republic of China.ORCID 0000-0002-6021-7282
Shiqi LuoDepartment of Entomology, College of Plant Protection, China Agricultural University, Beijing 100083, People's Republic of China.ORCID 0000-0002-0506-2230
Xin ZhouDepartment of Entomology, College of Plant Protection, China Agricultural University, Beijing 100083, People's Republic of China.ORCID 0000-0002-1407-7952
China Agricultural University · CNSanya University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Host specificity is observed in gut symbionts of diverse animal lineages. But how hosts maintain symbionts while rejecting their close relatives remains elusive. We use eusocial bees and their codiversified gut bacteria to understand host regulation driving symbiotic specificity. The cross-inoculation of bumblebee

Indexed as

BeesHost SpecificityImmunologic Deficiency SyndromesToll-Like ReceptorsAnimalsBacteriaDual OxidasesImmunityReactive Oxygen SpeciesDual OxidasesReactive Oxygen SpeciesToll-Like Receptorshoneybee gut microbehost immune responsehost specificityprostaglandinROS

Identifiers

PMID37556501
PMCPMC10438842
OpenAlexW4385693583

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.