Evidence map›Paper›PMID 37556304›Full record

ArticleEnvironmental health perspectives2023

Longitudinal Associations between Ambient Air Pollution and Angiogenic Biomarkers among Pregnant Women in the LIFECODES Study, 2006-2008.

Yi Zheng, Thomas McElrath, David Cantonwine, Hui Hu

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yi ZhengChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Thomas McElrathDivision of Maternal-Fetal Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
David CantonwineDivision of Maternal-Fetal Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Hui HuChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-7482-9060
Brigham and Women's Hospital · US

Funding

LIFECODES pregnancy cohortZIAES103321 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI FERGUSON, KELLY · 2016 to 2025
$6.1M
Hypertensive Disorders of Pregnancy and Early Risk of Maternal CVD: Influence of the External ExposomeK01HL153797 · NHLBI · UNIVERSITY OF FLORIDA · PI HU, HUI · 2021 to 2025
$874k
Intramural NIH HHS ZIA ES103321NHLBI NIH HHS K01 HL153797
6 · The paper itself

Abstract

backgroundExposures to ambient air pollution during pregnancy have been linked to adverse pregnancy outcomes such as preeclampsia and fetal growth restriction. Although evidence has shown that women with preeclampsia have higher ratio of soluble fms-like tyrosine kinase 1 to placental growth factor (sFlt-1/PlGF ratio), the potential impact of air pollution on markers of placental growth and function has not been well studied.

objectivesWe aimed to examine longitudinal associations between ambient air pollution exposure and angiogenic factors among pregnant women in LIFECODES, a prospective birth cohort and biorepository in Massachusetts in the United States.

methodsPlGF and sFlt-1 were measured among pregnant women using plasma samples collected around 10, 18, 26, and 35 wk' gestation. Women's exposures to ozone (

resultsA total of 1,066 pregnant women were included. In the multipollutant models, significant associations were observed for increased sFlt-1/PlGF ratio ( DISCUSSION: Exposures to

Indexed as

Air PollutionPre-EclampsiaBiomarkersFemaleHumansPlacentaPlacenta Growth FactorPregnancyPregnancy OutcomePregnant PeopleProspective StudiesVascular Endothelial Growth Factor Receptor-1BiomarkersPlacenta Growth FactorVascular Endothelial Growth Factor Receptor-1

Identifiers

PMID37556304
PMCPMC10411633
OpenAlexW4385690499

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.