Evidence map›Paper›PMID 37556084›Full record

ArticleJournal of experimental orthopaedics2023

Smoking and secondary ACL rupture are detrimental to knee health post ACL injury-a Bayesian analysis.

Micah Nicholls, Thorvaldur Ingvarsson, Stephanie Filbay, Stefan Lohmander, Kristin Briem

Open access · goldAbstract read
In one paragraph

Article in Journal of experimental orthopaedics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Micah NichollsFaculty of Medicine, Research Centre for Movement Sciences, The University of Iceland, Sæmundargata 2, Reykjavík, 102, Iceland. mkn1@hi.is.ORCID http://orcid.org/0000-0002-9569-6877
Thorvaldur IngvarssonDepartment of Orthopaedic Surgery, University of Akureyri, Akureyri, Iceland.
Stephanie FilbayDepartment of Physiotherapy, Faculty of Medicine Dentistry and Health Sciences, The University of Melbourne, Melbourne, Australia.
Stefan LohmanderDepartment of Clinical Sciences Lund, Orthopaedics, Lunds Universitet, Lund, Sweden.
Kristin BriemFaculty of Medicine, Research Centre for Movement Sciences, The University of Iceland, Sæmundargata 2, Reykjavík, 102, Iceland.
University of Iceland · ISLund University · SEThe University of Melbourne · AUUniversity of Akureyri · IS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify potential prognostic factors for patient-reported outcomes in an Icelandic cohort of ACL injured subjects.

methodsAll knee MRI reports written in Iceland between the years 2001 to 2011 were read to identify individuals with a possible ACL injury. These individuals were contacted and asked to complete an online questionnaire regarding their injury and current knee related health. The questionnaire collected information on years since surgery, injury circumstance, brace use, physiotherapy, ACL surgery, second ACL injury and current smoking status. In addition, the baseline status of their meniscii were assessed from the original MRI report and medical records were used to identify any subsequent, non-ACL surgery. The patient-reported Knee Osteoarthritis and Injury Outcome Score (KOOS) was used assess current knee related health. A Bayesian proportional odds model was used to assess the effect of all potential prognostic factors above as well as age and sex on KOOS outcomes.

resultsA total of 408 subjects completed the questionnaire indicating that they did rupture their ACL. The following variables were associated with worse outcomes across all KOOS subscales: having a subsequent arthroscopy, reinjury to your ACL, and smoking. Having physiotherapy for 9 months was associated with worse KOOS pain scores than having 6 months of physiotherapy. Conversely KOOS pain score tended to be higher if you injured your knee during sports.

conclusionReinjuring your ACL, smoking and having subsequent (non-ACLR) surgery predict your knee related health following an ACL injury. Strategies should be implemented to reduce the risk of secondary ACL injury, and patients should be strongly advised not to smoke.

Indexed as

ACL reconstructionBayesianKnee injuryNational cohortNonoperative managementPatient-reported outcomes

Identifiers

PMID37556084
PMCPMC10412518
OpenAlexW4385684861

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.