Evidence map›Paper›PMID 37555924›Full record

SynthesisBrain structure & function2023

Pain-related evoked potentials with concentric surface electrodes in patients and healthy subjects: a systematic review.

Laura Josephine Bubenzer, Lena Konsolke, Elena Enax-Krumova, Frederic Eberhardt, Martin Tegenthoff, Oliver Höffken, Özüm Simal Özgül

Open access · hybridAbstract readSystematic ReviewLetter
In one paragraph

Synthesis in Brain structure & function, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. A novel protocol to investigate the monoaminergic relationship between descending nociceptive and motor unit neuromodulation.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Laura Josephine Bubenzer *Department of Neurology, BG University Hospital Bergmannsheil gGmbH, Ruhr-University Bochum, Bürkle de La Camp-Platz 1, 44789, Bochum, Germany.
Lena Konsolke *Department of Neurology, BG University Hospital Bergmannsheil gGmbH, Ruhr-University Bochum, Bürkle de La Camp-Platz 1, 44789, Bochum, Germany.
Elena Enax-KrumovaDepartment of Neurology, BG University Hospital Bergmannsheil gGmbH, Ruhr-University Bochum, Bürkle de La Camp-Platz 1, 44789, Bochum, Germany.
Frederic EberhardtDepartment of Neurology, BG University Hospital Bergmannsheil gGmbH, Ruhr-University Bochum, Bürkle de La Camp-Platz 1, 44789, Bochum, Germany.
Martin TegenthoffDepartment of Neurology, BG University Hospital Bergmannsheil gGmbH, Ruhr-University Bochum, Bürkle de La Camp-Platz 1, 44789, Bochum, Germany.
Oliver HöffkenDepartment of Neurology, BG University Hospital Bergmannsheil gGmbH, Ruhr-University Bochum, Bürkle de La Camp-Platz 1, 44789, Bochum, Germany.
Özüm Simal ÖzgülDepartment of Neurology, BG University Hospital Bergmannsheil gGmbH, Ruhr-University Bochum, Bürkle de La Camp-Platz 1, 44789, Bochum, Germany. oezuem.oezguel@rub.de.ORCID https://orcid.org/0000-0002-3573-7892
BG University Hospital Bergmannsheil Bochum · DE

Funding

Deutsche Forschungsgemeinschaft SFB 874/A1 and A5, Project No.: 122679504.Ruhr University Bochum, FoRUM K120-18
6 · The paper itself

Abstract

Pain-related evoked potentials with concentric surface electrodes (PREP with CE) have been increasingly used in the diagnostics of polyneuropathies as well as in pain research. However, the study results are partly inconsistent regarding their utility to distinguish between normal and abnormal findings. The present systematic review aimed to summarise and compare study results, where PREP with CE were used in healthy subjects or patients and to identify possible influencing factors. We found 36 research articles, of which 21 investigated disorders in patients compared to healthy controls, while the other 15 focussed on basic research in healthy subjects. Patients with polyneuropathies showed the most consistent PREP results with similar prolonged latencies and reduced amplitude values. Findings in other patient groups or in healthy subjects were more heterogeneous. There was evidence for an influence by age and height as well as by central effects like emotions, which should be considered in further studies. Further systematic research analysing PREP results depending on individual and disease-specific factors is needed to develop optimal normative values.

Indexed as

Evoked PotentialsPolyneuropathiesElectrodesHealthy VolunteersHumansPainConcentric surface electrodesDiagnostic toolElectrophysiological measuresNeuropathyPain-related evoked potentials

Identifiers

PMID37555924
PMCPMC10471670
OpenAlexW4385684432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.