Evidence map›Paper›PMID 37555890›Full record

ArticleCancer2023

Alcohol consumption and prognosis and survival in breast cancer survivors: The Pathways Study.

Marilyn L Kwan, Emily Valice, Isaac J Ergas, Janise M Roh, Bette J Caan, Elizabeth M Cespedes Feliciano, Tatjana Kolevska, Terryl J Hartman, Charles P Quesenberry, Christine B Ambrosone and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Marilyn L KwanDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.ORCID 0000-0001-8863-3950
Emily ValiceDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Isaac J ErgasDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.ORCID 0000-0002-3187-9754
Janise M RohDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Bette J CaanDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Elizabeth M Cespedes FelicianoDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.ORCID 0000-0003-1192-4017
Tatjana KolevskaDepartment of Oncology, Kaiser Permanente Vallejo Medical Center, Vallejo, California, USA.
Terryl J HartmanDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Charles P QuesenberryDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Christine B AmbrosoneDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Lawrence H KushiDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Kaiser Permanente · USEmory University · USKaiser Permanente Vallejo Medical Center · USRoswell Park Comprehensive Cancer Center · US

Funding

Prospective Study of Breast Cancer SurvivorshipR01CA105274 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI KUSHI, LAWRENCE H · 2004 to 2014
$19.9M
Infrastructure for Pathways, a Prospective Study of Breast Cancer SurvivorshipU01CA195565 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI AMBROSONE, CHRISTINE B., KUSHI, LAWRENCE H · 2016 to 2025
$18.8M
NCI NIH HHS R01 CA105274NCI NIH HHS R01CA105274NCI NIH HHS U01 CA195565NCI NIH HHS U01CA195565
6 · The paper itself

Abstract

backgroundThe impact of alcohol consumption on breast cancer (BC) prognosis remains unclear.

methodsThe authors examined short-term alcohol intake in relation to recurrence and mortality in 3659 women who were diagnosed with stage I-IV BC from 2003 to 2013 in the Pathways Study. Alcohol drinking in the past 6 months was assessed at cohort entry (mean, 2 months postdiagnosis) and 6 months later using a food-frequency questionnaire. Study end points were recurrence and death from BC, cardiovascular disease, and all causes. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using multivariable Cox proportional hazards models.

resultsOver an average follow-up of 11.2 years, 524 recurrences and 834 deaths (369 BC-specific and 314 cardiovascular disease-specific) occurred. Compared with nondrinkers (36.9%), drinkers were more likely younger, more educated, and current or past smokers. Overall, alcohol consumption was not associated with recurrence or mortality. However, women with higher body mass index (BMI ≥ 30 kg/m

conclusionsAlcohol drinking around the time of and up to 6 months after BC diagnosis was associated with lower risk of all-cause mortality in obese women. A possible higher risk of recurrence was observed in nonobese women.

Indexed as

Breast NeoplasmsCancer SurvivorsCardiovascular DiseasesAlcohol DrinkingFemaleHumansPrognosisProportional Hazards ModelsRisk Factorsalcoholbreast cancerestrogenethanolmortalityprognosisrecurrence

Identifiers

PMID37555890
PMCPMC10840903
OpenAlexW4385683717

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.