ArticleJournal of the American Medical Informatics Association : JAMIA2023
An open natural language processing (NLP) framework for EHR-based clinical research: a case demonstration using the National COVID Cohort Collaborative (N3C).
Article in Journal of the American Medical Informatics Association : JAMIA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- A multi-site benchmarking framework for scalable extraction of geriatric care constructs from electronic health records.npj health systems · 2026Article
- A High-Accuracy Rule-Based Algorithm for Automated Extraction of Coronary Artery Calcium Scores from Mixed-Language Radiology Reports.Journal of imaging informatics in medicine · 2026Article
- A dynamic risk prediction framework for Alzheimer's disease and related dementias with interpretability.NPJ digital medicine · 2026Article
- A Self-Explainable Dynamic Risk Monitoring Framework for Predicting Alzheimer's Disease and Related Dementias.medRxiv : the preprint server for health sciences · 2025Article
- A natural language processing pipeline for identifying pediatric long COVID symptoms and functional impacts in freeform clinical notes: a RECOVER study.JAMIA open · 2025Article
- Using Electronic Health Records to Classify Cancer Site and Metastasis.Applied clinical informatics · 2025Article
- A scoping review of OMOP CDM adoption for cancer research using real world data.NPJ digital medicine · 2025Article
- Assessing Total Hip Arthroplasty Outcomes and Generating an Orthopedic Research Outcome Database via a Natural Language Processing Pipeline: Development and Validation Study.JMIR medical informatics · 2025Article
- Development and Validation of Natural Language Processing Algorithms in the ENACT National Electronic Health Record Research Network.medRxiv : the preprint server for health sciences · 2025Article
- Article
- Bibliometric analysis of artificial intelligence in healthcare research: Trends and future directions.Future healthcare journal · 2024Article
- A taxonomy for advancing systematic error analysis in multi-site electronic health record-based clinical concept extraction.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- Assertion Detection in Clinical Natural Language Processing using Large Language Models.Proceedings. IEEE International Conference on Healthcare Informatics · 2024Article
- ReDWINE: A clinical datamart with text analytical capabilities to facilitate rehabilitation research.International journal of medical informatics · 2023Article
- Representing and utilizing clinical textual data for real world studies: An OHDSI approach.Journal of biomedical informatics · 2023Article
- A comprehensive update on CIDO: the community-based coronavirus infectious disease ontology.Journal of biomedical semantics · 2022Article
- Multicenter Validation of Natural Language Processing Algorithms for the Detection of Common Data Elements in Operative Notes for Total Hip Arthroplasty: Algorithm Development and Validation.JMIR medical informatics · 2022Article
- Article
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Authors and funding
28 authors.
Funding
Abstract
Despite recent methodology advancements in clinical natural language processing (NLP), the adoption of clinical NLP models within the translational research community remains hindered by process heterogeneity and human factor variations. Concurrently, these factors also dramatically increase the difficulty in developing NLP models in multi-site settings, which is necessary for algorithm robustness and generalizability. Here, we reported on our experience developing an NLP solution for Coronavirus Disease 2019 (COVID-19) signs and symptom extraction in an open NLP framework from a subset of sites participating in the National COVID Cohort (N3C). We then empirically highlight the benefits of multi-site data for both symbolic and statistical methods, as well as highlight the need for federated annotation and evaluation to resolve several pitfalls encountered in the course of these efforts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.