Evidence map›Paper›PMID 37555802›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Topical Drug Delivery of Concentrated Cabazitaxel in an α-Tocopherol and DMSO Solution.

Boyang Sun, Georgios Paraskevopoulos, Jiwei Min, Robert Rossdeutcher, Sanjana Ghosh, Breandan Quinn, Meng-Hsuan Lin, Debanjan Sarkar, Dinesh Sukumaran, Yuefei Wang and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  5. Topical Drug Delivery of Concentrated Cabazitaxel in an α-Tocopherol and DMSO Solution.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Boyang SunSchool of Chemical Engineering and Technology, Key Laboratory of Systems Bioengineering (Ministry of Education), Frontiers Science Center for Synthetic Biology (Ministry of Education), State Key Laboratory of Chemical Engineering, Tianjin University, Tianjin, 300350, P. R. China.
Georgios ParaskevopoulosSkin Barrier Research Group, Faculty of Pharmacy, Charles University, Akademika Heyrovského 1203, Hradec Králové, 50005, Czech Republic.
Jiwei MinSchool of Chemical Engineering and Technology, Key Laboratory of Systems Bioengineering (Ministry of Education), Frontiers Science Center for Synthetic Biology (Ministry of Education), State Key Laboratory of Chemical Engineering, Tianjin University, Tianjin, 300350, P. R. China.
Robert RossdeutcherDepartment of Chemistry, State University of New York at Buffalo, Buffalo, NY, 14260, USA.
Sanjana GhoshDepartment of Biomedical Engineering, State University of New York at Buffalo, Buffalo, NY, 14260, USA.
Breandan QuinnDepartment of Biomedical Engineering, State University of New York at Buffalo, Buffalo, NY, 14260, USA.
Meng-Hsuan LinDepartment of Biomedical Engineering, State University of New York at Buffalo, Buffalo, NY, 14260, USA.
Debanjan SarkarDepartment of Biomedical Engineering, State University of New York at Buffalo, Buffalo, NY, 14260, USA.
Dinesh SukumaranDepartment of Chemistry, State University of New York at Buffalo, Buffalo, NY, 14260, USA.
Yuefei WangSchool of Chemical Engineering and Technology, Key Laboratory of Systems Bioengineering (Ministry of Education), Frontiers Science Center for Synthetic Biology (Ministry of Education), State Key Laboratory of Chemical Engineering, Tianjin University, Tianjin, 300350, P. R. China.ORCID 0000-0002-5736-7431
Kateřina VávrováSkin Barrier Research Group, Faculty of Pharmacy, Charles University, Akademika Heyrovského 1203, Hradec Králové, 50005, Czech Republic.ORCID 0000-0002-8502-4372
Jonathan F LovellDepartment of Biomedical Engineering, State University of New York at Buffalo, Buffalo, NY, 14260, USA.ORCID 0000-0002-9052-884X
Yumiao ZhangSchool of Chemical Engineering and Technology, Key Laboratory of Systems Bioengineering (Ministry of Education), Frontiers Science Center for Synthetic Biology (Ministry of Education), State Key Laboratory of Chemical Engineering, Tianjin University, Tianjin, 300350, P. R. China.ORCID 0000-0002-6166-0470
Buffalo State University · USMinistry of Education of the People's Republic of China · CNCharles University · CZ

Funding

CSRD VA 1
6 · The paper itself

Abstract

Topical chemotherapy approaches are relevant for certain skin cancer treatments. This study observes that cabazitaxel (CTX), a broad-spectrum second-generation taxane cytotoxic agent, can be dissolved in α-tocopherol at high concentrations exceeding 100 mg mL

Indexed as

alpha-TocopherolSkin NeoplasmsAnimalsDimethyl SulfoxideHumansMiceMice, NudeTaxoidsalpha-TocopherolcabazitaxelDimethyl SulfoxideTaxoidscabazitaxelskin cancertransdermal deliveryα-tocopherol

Identifiers

PMID37555802
PMCPMC10582425
OpenAlexW4385683980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.