ArticleTranslational vision science & technology2023
Disagreement of Radial Peripapillary Capillary Density Among Four Optical Coherence Tomography Angiography Devices.
Article in Translational vision science & technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- The Inter-Eye Differences of the Circumpapillary Microvasculature in Primary Open-Angle Glaucoma.Translational vision science & technology · 2026Article
- Differentiating Alzheimer's disease and vascular dementia via combined OCT and OCT‑angiography analysis.Scientific reports · 2026Article
- Alterations in blood flow at the optic nerve head in patients with thyroid eye disease using optic coherence tomography angiography.Frontiers in medicine · 2025Article
- Impact of smoking on choroidal microvasculature dropout in glaucoma: a cross-sectional study.BMJ open ophthalmology · 2023Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This prospective study evaluated the agreement among four optical coherence tomography angiography (OCTA) devices in the assessment of radial peripapillary capillary (RPC) density. Methods: The study included 48 eyes of 48 subjects (14 healthy, 19 glaucomatous, and 15 non-glaucomatous optic neuropathy). Each participant was scanned using four OCTA devices in a random sequence: RTVue XR Avanti (RTVue), DRI OCT Triton (Triton), Revo NX 130 (Revo), and PLEX Elite 9000 (PlexE). All 6 × 6-mm grayscale OCTA images from each device were analyzed for RPC density using a customized algorithm. Agreement between each pair of devices was assessed using intraclass correlation coefficients (ICCs) and Bland-Altman plots. Results: There was a poor correlation between devices in all comparisons (RTVue-Triton, ICC = 0.34; RTVue-Revo, ICC = 0.31; RTVue-PlexE, ICC = 0.28; Triton-Revo, ICC = 0.31; Triton-PlexE, ICC = 0.17; Revo-PlexE, ICC = 0.34). Significant proportional biases (P < 0.05) and wide limits of agreement with apparent constant biases were identified in all comparisons. The mean difference was greatest for the RTVue-Revo pair (-49.3%; 95% confidence interval [CI], -52.9 to -45.8) and smallest for the Triton-PlexE pair (-7.7%; 95% CI, -10.1 to -5.3). Conclusions: The RPC densities obtained from each device had poor inter-device agreement and significant biases and cannot be used interchangeably. Translational Relevance: RPC density obtained from different OCTA devices is not interchangeable; thus, the progression of optic neuropathy should be monitored using the same OCTA device.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.