ArticleFrontiers in neuroimaging2022
Automatic measure and normalization of spinal cord cross-sectional area using the pontomedullary junction.
Article in Frontiers in neuroimaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 25 citations in OpenAlex.
- A lightweight method for regression-based normalization of the cross-sectional area for cervical spinal cord atrophy assessment.Medical & biological engineering & computing · 2026Article
- Adult-Lifespan Segment-Specific Normative Atlas of Cervical Spinal Cord Morphology, With Exploratory Application in Degenerative Cervical Myelopathy.Neurospine · 2026Article
- Early and Progressive Spinal Cord Atrophy in Spinocerebellar Ataxia Type 1.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis.Annals of clinical and translational neurology · 2026Article
- Charting Cervical Spinal Cord Morphometry Across the Lifespan.bioRxiv : the preprint server for biology · 2026Article
- Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS.Annals of clinical and translational neurology · 2026Article
- Spinal nerves as landmarks for spinal cord segment delineation: cervical cross-sectional area measurement in healthy subjects.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Spinal cord involvement and cardiovascular autonomic dysfunction in Parkinson's disease.Scientific reports · 2026Article
- Length relationships between vertebral column and spinal cord: differential contributions of the cervical, thoracic and lumbosacral regions.Surgical and radiologic anatomy : SRA · 2025Article
- Super-Resolution in Clinically Available Spinal Cord MRIs Enables Automated Atrophy Analysis.AJNR. American journal of neuroradiology · 2025Article
- Body size and intracranial volume interact with the structure of the central nervous system: A multi-center in vivo neuroimaging study.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Rootlets-based registration to the PAM50 spinal cord template.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Fully-automated estimation of upper cervical cord cross-sectional area using pontomedullary junction referencing in multiple sclerosis.Frontiers in neuroimaging · 2025Article
- Optimization of cervical cord atrophy measurement using a real-world, multicentre dataset in multiple sclerosis.Frontiers in neurology · 2025Article
- Cervical spinal cord morphometrics in degenerative cervical myelopathy: quantification using semi-automated normalized technique and correlation with neurological dysfunctions.The spine journal : official journal of the North American Spine Society · 2024Article
- Reproducible Spinal Cord Quantitative MRI Analysis with the Spinal Cord Toolbox.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024Review
- A database of the healthy human spinal cord morphometry in the PAM50 template space.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Spinal cord evaluation in multiple sclerosis: clinical and radiological associations, present and future.Brain communications · 2024Review
- Automatic segmentation of the spinal cord nerve rootlets.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Pontomedullary junction as a reference for spinal cord cross-sectional area: validation across neck positions.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Spinal cord cross-sectional area (CSA) is a relevant biomarker to assess spinal cord atrophy in neurodegenerative diseases. However, the considerable inter-subject variability among healthy participants currently limits its usage. Previous studies explored factors contributing to the variability, yet the normalization models required manual intervention and used vertebral levels as a reference, which is an imprecise prediction of the spinal levels. In this study we implemented a method to measure CSA automatically from a spatial reference based on the central nervous system (the pontomedullary junction, PMJ), we investigated factors to explain variability, and developed normalization strategies on a large cohort (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.