Evidence map›Paper›PMID 37555140›Full record

ArticleFrontiers in neuroimaging2022

Control-theoretic integration of stimulation and electrophysiology for cognitive enhancement.

Matthew F Singh, Michael W Cole, Todd S Braver, ShiNung Ching

Open access · diamondAbstract read
In one paragraph

Article in Frontiers in neuroimaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Matthew F SinghElectrical and Systems Engineering, Washington University in St. Louis, St. Louis, MO, United States.
Michael W ColeCenter for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ, United States.
Todd S BraverPsychological and Brain Science, Washington University in St. Louis, St. Louis, MO, United States.
ShiNung ChingElectrical and Systems Engineering, Washington University in St. Louis, St. Louis, MO, United States.
Washington University in St. Louis · USRutgers, The State University of New Jersey · US

Funding

BIOMEDICAL RESEARCH TRAINING IN DRUG ABUSET32DA007261 · NIDA · WASHINGTON UNIVERSITY · PI ARPANA AGRAWAL, Jose A Moron-Concepcion · 1991 to 2026
$8.8M
Cognitive enhancement through model-based and individualized neurostimulationR21MH132240 · NIMH · WASHINGTON UNIVERSITY · PI BRAVER, TODD S, CHING, SHINUNG · 2023 to 2024
$429k
NIDA NIH HHS T32 DA007261NIMH NIH HHS R21 MH132240
6 · The paper itself

Abstract

Transcranial electrical stimulation (tES) technology and neuroimaging are increasingly coupled in basic and applied science. This synergy has enabled individualized tES therapy and facilitated causal inferences in functional neuroimaging. However, traditional tES paradigms have been stymied by relatively small changes in neural activity and high inter-subject variability in cognitive effects. In this perspective, we propose a tES framework to treat these issues which is grounded in dynamical systems and control theory. The proposed paradigm involves a tight coupling of tES and neuroimaging in which M/EEG is used to parameterize generative brain models as well as control tES delivery in a hybrid closed-loop fashion. We also present a novel quantitative framework for cognitive enhancement driven by a new computational objective: shaping how the brain reacts to potential "inputs" (e.g., task contexts) rather than enforcing a fixed pattern of brain activity.

Indexed as

brain dynamicscognitive enhancementcontrol theory and control engineeringneurostimulationtranscranial electric stimulation

Identifiers

PMID37555140
PMCPMC10406304
OpenAlexW4309280958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.