Evidence map›Paper›PMID 37554993›Full record

ArticleData in brief2023

Anti-inflammatory cytokine stimulation of HMC3 cells: Proteome dataset.

Shreya Ahuja, Iulia M Lazar

Abstract read
In one paragraph

Article in Data in brief, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shreya AhujaDepartment of Biological Sciences, Virgina Tech, USA.
Iulia M LazarDepartment of Biological Sciences, Virgina Tech, USA.

Funding

Microfluidic Chip for the Analysis of Cell-Surface ProteinsR01GM121920 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI LAZAR, MARIA IULIANA · 2017 to 2021
$1.9M
NIGMS NIH HHS R01 GM121920
6 · The paper itself

Abstract

The immunoprotective functions of microglia in the brain are mediated by the inflammatory M1 phenotype. This phenotype is challenged by anti-inflammatory cytokines which polarize the microglia cells to an immunosuppressive M2 phenotype, a trait that is often exploited by cancer cells to evade immune recognition and promote tumor growth. Investigating the molecular determinants of this behavior is crucial for advancing the understanding of the mechanisms that cancer cells use to escape immune attack. In this article, we describe liquid chromatography (LC)-mass spectrometry (MS)/proteomic data acquired with an EASY-nanoLC 1200-Q Exactive

Indexed as

Anti-inflammatory cytokinesCancerMicrogliaProteomics

Identifiers

PMID37554993
PMCPMC10404857

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.