Evidence map›Paper›PMID 37554665›Full record

ArticleRadiology case reports2023

Cerebellar, hippocampal, and basal nuclei transient edema with restricted diffusion (CHANTER) syndrome in the setting of opioid and phencyclidine use.

Muhammed F Atac, George K Vilanilam, Prashanth Reddy Damalcheruvu, Ishan Pandey, Surjith Vattoth

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Frozen in Addiction: A New Wave of Drug-Induced Movement Disorders?Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
  2. CHANTER syndrome: an under-recognized cause of reversible hydrocephalus after opioid overdose.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muhammed F AtacDivision of Neuroradiology, Department of Radiology, University of Arkansas for Medical Sciences, 4301 W Markham St., Slot 556, Little Rock, AR, 72205 USA.
George K VilanilamDivision of Neuroradiology, Department of Radiology, University of Arkansas for Medical Sciences, 4301 W Markham St., Slot 556, Little Rock, AR, 72205 USA.
Prashanth Reddy DamalcheruvuDivision of Neuroradiology, Department of Radiology, University of Arkansas for Medical Sciences, 4301 W Markham St., Slot 556, Little Rock, AR, 72205 USA.
Ishan PandeyPre Medicine Professional Track, Baylor University, Waco, TX, 76706, USA.
Surjith VattothDivision of Neuroradiology, Department of Radiology, University of Arkansas for Medical Sciences, 4301 W Markham St., Slot 556, Little Rock, AR, 72205 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebellar, hippocampal, and basal nuclei transient edema with restricted diffusion (CHANTER) syndrome is a constellation of specific imaging findings characterized by cytotoxic edema in the bilateral hippocampi, cerebellar cortices, and basal ganglia in patients presenting with altered mental status in the setting of substance intoxication. Previous case reports have demonstrated a strong correlation between CHANTER syndrome and polysubstance abuse, particularly with opioid intoxication. The patient we present in this case was found unresponsive following opioid use and demonstrated a constellation of findings on initial and follow-up imaging, consistent with CHANTER syndrome. While cases of irreversible brain damage or death during hospitalization have been reported in the literature, our patient demonstrated near-full recovery a few days after admission to the hospital. We aim to highlight the presentation and progression of CHANTER syndrome and alert clinicians and radiologists to include this entity in their diagnostic checklist for patients with polysubstance abuse and altered mental status.

Indexed as

Basal gangliaCerebellumCHANTERHippocampiLeukoencephalopathyOpioid intoxication

Identifiers

PMID37554665
PMCPMC10405156

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.