Evidence map›Paper›PMID 37554451›Full record

ArticleiScience2023

Plasma proteomic signatures of enteric permeability among hospitalized and community children in Kenya and Pakistan.

Kirkby D Tickell, Donna M Denno, Ali Saleem, Zaubina Kazi, Benson O Singa, Catherine Achieng, Charles Mutinda, Barbra A Richardson, Kristjana H Ásbjörnsdóttir, Stephen E Hawes and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kirkby D TickellDepartment of Global Health, University of Washington, Seattle, WA, USA.
Donna M DennoDepartment of Global Health, University of Washington, Seattle, WA, USA.
Ali SaleemThe Childhood Acute Illness & Nutrition (CHAIN) Network, Nairobi, Kenya.
Zaubina KaziThe Childhood Acute Illness & Nutrition (CHAIN) Network, Nairobi, Kenya.
Benson O SingaThe Childhood Acute Illness & Nutrition (CHAIN) Network, Nairobi, Kenya.
Catherine AchiengThe Childhood Acute Illness & Nutrition (CHAIN) Network, Nairobi, Kenya.
Charles MutindaThe Childhood Acute Illness & Nutrition (CHAIN) Network, Nairobi, Kenya.
Barbra A RichardsonDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
Kristjana H ÁsbjörnsdóttirDepartment of Epidemiology, University of Iceland, Reykjavik, Iceland.
Stephen E HawesDepartment of Epidemiology, University of Washington, Seattle, WA, USA.
James A BerkleyThe Childhood Acute Illness & Nutrition (CHAIN) Network, Nairobi, Kenya.
Judd L WalsonDepartment of Global Health, University of Washington, Seattle, WA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to establish if enteric permeability was associated with similar biological processes in children recovering from hospitalization and relatively healthy children in the community. Extreme gradient boosted models predicting the lactulose-rhamnose ratio (LRR), a biomarker of enteric permeability, using 7,500 plasma proteins and 34 fecal biomarkers of enteric infection among 89 hospitalized and 60 community children aged 2-23 months were built. The R

Indexed as

OutcomePatient characteristicsPediatricsProteomics

Identifiers

PMID37554451
PMCPMC10405056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.