Evidence map›Paper›PMID 37554200›Full record

ReviewGenes & diseases2023

Coactivator-associated arginine methyltransferase 1: A versatile player in cell differentiation and development.

Zhongrui Ma, Xinxing Lyu, Ning Qin, Haoyu Liu, Mengrui Zhang, Yongchao Lai, Bo Dong, Peiyuan Lu

Abstract readReview
In one paragraph

Review in Genes & diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhongrui MaMedical Research Center, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong 250014, China.
Xinxing LyuMedical Research Center, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong 250014, China.
Ning QinDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China.
Haoyu LiuDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China.
Mengrui ZhangDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China.
Yongchao LaiMedical Research Center, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong 250014, China.
Bo DongDepartment of Cardiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China.
Peiyuan LuMedical Research Center, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong 250014, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein arginine methylation is a common post-translational modification involved in the regulation of various cellular functions. Coactivator-associated arginine methyltransferase 1 (CARM1) is a protein arginine methyltransferase that asymmetrically dimethylates histone H3 and non-histone proteins to regulate gene transcription. CARM1 has been found to play important roles in cell differentiation and development, cell cycle progression, autophagy, metabolism, pre-mRNA splicing and transportation, and DNA replication. In this review, we describe the molecular characteristics of CARM1 and summarize its roles in the regulation of cell differentiation and development in mammals.

Indexed as

Arginine methylationCARM1Cell differentiationDevelopmentEpigenetic regulation

Identifiers

PMID37554200
PMCPMC10404874

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.