Evidence map›Paper›PMID 37554075›Full record

ArticleJournal of stroke2023

Association of Unfavorable Social Determinants of Health With Stroke/Transient Ischemic Attack and Vascular Risk Factors in Hispanic/Latino Adults: Results From Hispanic Community Health Study/Study of Latinos.

Gabriela Trifan, Linda C Gallo, Melissa Lamar, Olga Garcia-Bedoya, Krista M Perreira, Amber Pirzada, Gregory A Talavera, Sylvia W Smoller, Carmen R Isasi, Jianwen Cai and 2 more

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Journal of stroke, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06970210 (United4Stroke), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06970210 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

United4Stroke (U4S) - El Paso Network: Community Health Program With Group-Based Education

TypeinterventionalSponsorUniversity of Texas, El PasoRan2025 to 2028Enrolled46ConditionsStrokeArmsGroup-Based Education, Individualized Coaching
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Social determinants of health and stroke risk: A dose-response analysis of cumulative socioeconomic burden in US adults.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  5. "Interpreters don't tell you everything": experiences with medical interpretation among Latino cancer patients and caregivers with limited English proficiency.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  6. Article
  7. Article
  8. Equitable Stroke Care for a Growing Population: The Need for Cultural Sensitivity.Circulation. Cardiovascular quality and outcomes · 2025
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Gabriela TrifanDepartment of Neurology and Rehabilitation, University of Illinois at Chicago College of Medicine, Chicago, IL, USA.
Linda C GalloDepartment of Psychology, San Diego State University, San Diego, CA, USA.
Melissa LamarRush Alzheimer's Disease Center and Department of Psychiatry and Behavioral Sciences, Rush University, Chicago, IL, USA.
Olga Garcia-BedoyaDepartment of Medicine, Institute for Minority Health Research, University of Illinois at Chicago, Chicago, IL, USA.
Krista M PerreiraDepartment of Social Medicine, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Amber PirzadaDepartment of Medicine, Institute for Minority Health Research, University of Illinois at Chicago, Chicago, IL, USA.
Gregory A TalaveraDepartment of Psychology, San Diego State University, San Diego, CA, USA.
Sylvia W SmollerDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Carmen R IsasiDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Jianwen CaiDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Martha L DaviglusDepartment of Medicine, Institute for Minority Health Research, University of Illinois at Chicago, Chicago, IL, USA.
Fernando D TestaiDepartment of Neurology and Rehabilitation, University of Illinois at Chicago College of Medicine, Chicago, IL, USA.
University of Illinois Chicago · USAlbert Einstein College of Medicine · USSan Diego State University · USUniversity of North Carolina at Chapel Hill · US

Funding

Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Culturally relevant contributors to cognitive and MRI changes in older LatinosR01AG062711 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LAMAR, MELISSA · 2020 to 2025
$3.6M
HISPANIC COMMUNITY HEALTH STUDY-268065233N01HC065233 · HC · COORDINATING CENTER · PI CHAMBLESS, LLOYD E · 2006 to 2006
–
NHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NHLBI NIH HHS R01 AG062711NIA NIH HHS R01 AG062711NIDCD NIH HHSNIDCR NIH HHSNIDDK NIH HHSNIEHS NIH HHS P30 ES027792NIMHD NIH HHSNINDS NIH HHS
6 · The paper itself

Abstract

background and purposeSocial determinants of health (SDOH) are non-medical factors that may contribute to the development of diseases, with a higher representation in underserved populations. Our objective is to determine the association of unfavorable SDOH with self-reported stroke/transient ischemic attack (TIA) and vascular risk factors (VRFs) among Hispanic/Latino adults living in the US.

methodsWe used cross-sectional data from the Hispanic Community Health Study/Study of Latinos. SDOH and VRFs were assessed using questionnaires and validated scales and measurements. We investigated the association between the SDOH (individually and as count: ≤1, 2, 3, 4, or ≥5 SDOH), VRFs and stroke/TIA using regression analyses.

resultsFor individuals with stroke/TIA (n=388), the mean age (58.9 years) differed from those without stroke/TIA (n=11,210; 46.8 years; P<0.0001). In bivariate analysis, income <$20,000, education less than high school, no health insurance, perceived discrimination, not currently employed, upper tertile for chronic stress, and lower tertiles for social support and language- and social-based acculturation were associated with stroke/TIA and retained further. A higher number of SDOH was directly associated with all individual VRFs investigated, except for at-risk alcohol, and with number of VRFs (β=0.11, 95% confidence interval [CI]=0.09-0.14). In the fully adjusted model, income, discrimination, social support, chronic stress, and employment status were individually associated with stroke/TIA; the odds of stroke/TIA were 2.3 times higher in individuals with 3 SDOH (95% CI 1.6-3.2) and 2.7 times (95% CI 1.9-3.7) for those with ≥5 versus ≤1 SDOH.

conclusionAmong Hispanic/Latino adults, a higher number of SDOH is associated with increased odds for stroke/TIA and VRFs. The association remained significant after adjustment for VRFs, suggesting involvement of non-vascular mechanisms.

Indexed as

Social determinant of healthStrokeVascular risk factors

Identifiers

PMID37554075
PMCPMC10574305
OpenAlexW4385684533

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.