Evidence map›Paper›PMID 37553801›Full record

ArticleJournal of viral hepatitis2023

Cascade of care among people with hepatitis B in New South Wales, Australia.

Syed Hassan Bin Usman Shah, Heather Valerio, Behzad Hajarizadeh, Gail Matthews, Maryam Alavi, Gregory J Dore

Abstract read
In one paragraph

Article in Journal of viral hepatitis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Syed Hassan Bin Usman ShahViral Hepatitis Clinical Research Program (VHCRP), The Kirby Institute, UNSW, Sydney, Australia.ORCID 0000-0003-4205-1140
Heather ValerioViral Hepatitis Clinical Research Program (VHCRP), The Kirby Institute, UNSW, Sydney, Australia.
Behzad HajarizadehViral Hepatitis Clinical Research Program (VHCRP), The Kirby Institute, UNSW, Sydney, Australia.ORCID 0000-0003-2212-2028
Gail MatthewsViral Hepatitis Clinical Research Program (VHCRP), The Kirby Institute, UNSW, Sydney, Australia.
Maryam AlaviViral Hepatitis Clinical Research Program (VHCRP), The Kirby Institute, UNSW, Sydney, Australia.
Gregory J DoreViral Hepatitis Clinical Research Program (VHCRP), The Kirby Institute, UNSW, Sydney, Australia.

Funding

Department of Health and Aged Care, Australian GovernmentNational Health and Medical Research CouncilNew South Wales Ministry of Health
6 · The paper itself

Abstract

Hepatitis B virus (HBV) care cascade characterisation is important for monitoring HBV elimination progress. This study evaluated care cascade and factors associated with HBV DNA testing and treatment in New South Wales, Australia. HBV care cascade were determined through linkage of HBV notifications (1993-2017) to Medicare and pharmaceutical benefits schemes (2010-2018). Timely HBV DNA testing was within 4 weeks of HBV notification. Multivariate Cox proportional hazards regression evaluated factors associated with HBV DNA testing and treatment. Among 15,202 people with HBV notification, 10,479 (69%) were tested for HBV DNA. A total of 3179 (21%) initiated HBV treatment. HBV DNA testing was more likely among age ≥45 years (adjusted hazard ratio [aHR] 1.07, 95% CI: 1.02, 1.12), hepatocellular carcinoma (HCC) (aHR 1.23, 95% CI: 1.01, 1.50), coinfection (aHR 1.61, 95% CI: 1.23, 2.09), later notification (2014-2017) (aHR 1.21, 95% CI: 1.16, 1.26) and less likely among females (aHR 0.95, 95% CI: 0.91, 0.99), history of alcohol use disorder (AUD) (aHR 0.77, 95% CI: 0.66, 0.89), HCV coinfection (aHR .62, 95% CI: 0.55, 0.70) and Indigenous peoples (aHR 0.84, 95% CI: 0.71, 0.98). HBV treatment was associated with age ≥45 years (aHR 1.35, 95% CI: 1.24, 1.48), decompensated cirrhosis (aHR 2.07, 95% CI: 1.62, 2.65), HCC (aHR 2.96, 95% CI: 2.35, 3.74), HIV coinfection (aHR 4.27, 95% CI: 3.43, 5.31) and later notification (2014-2017) (aHR 1.37, 95% CI: 1.26, 1.47). HBV treatment was less likely among females (aHR 0.68, 95% CI: 0.63, 0.73) and Indigenous peoples (aHR 0.58, 95% CI: 0.42, 0.80). HBV DNA testing and treatment coverage have increased, but remain sub-optimal among some key populations.

Indexed as

Carcinoma, HepatocellularCoinfectionHepatitis BLiver NeoplasmsAgedAustraliaDNA, ViralFemaleHepatitis B virusHumansMiddle AgedNational Health ProgramsNew South WalesDNA, Viralcare cascadedata linkageHBV DNA testinghepatitis B virustreatment uptake

Identifiers

PMID37553801
PMCPMC10946799

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.