ArticleChinese neurosurgical journal2023
Surgical site infections after elective craniotomy for brain tumor: a study on potential risk factors and related treatments.
Article in Chinese neurosurgical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- A meta-analysis of the risk factors for neurosurgical surgical site infection following craniotomy.International wound journal · 2024Pooled it
- Surgical Site Infections After External Ventricular Drain Placement: Incidence, Patient-Related, and Periprocedural Risk Factors.Neurosurgery practice · 2026Article
- Review
- Beyond the Knot: A Pragmatic Comparison of Monocryl and Prolene for Neurosurgical Wound Closure.Cureus · 2026Article
- Postoperative Pain Trajectories After Craniotomy in Brain Tumor Patients: A Cross-Sectional Study of Intensity and Characteristics.Medicina (Kaunas, Lithuania) · 2025Article
- Incidence of surgical site infections in cerebrovascular surgery: systemic risk factors.Brain & spine · 2025Article
- Scalp necrosis following preoperative endovascular embolisation of the superficial temporal artery for meningioma.BMJ case reports · 2024Article
- Comprehensive analysis of risk factors and pathogenetic characteristics associated with surgical site infections following craniotomy procedures.International wound journal · 2024Article
- A review on wound management strategies in enhanced recovery after craniotomy: An in-depth analysis of their influence on patient recovery and surgical outcomes.International wound journal · 2024Review
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurgical site infection (SSI) is a common complication following craniotomy that increases morbidity, mortality, and medical expenses. The objectives of this study were to determine the relevant risk factors associated with SSI after elective craniotomy for brain tumor and analyse the treatments for SSI.
methodsA retrospective nested case‒control study was conducted using data from patients who underwent craniotomy for brain tumor resection at the Neurosurgical Oncology Department No. 6 of Beijing Tiantan Hospital, Capital Medical University, between January 2019 and December 2021. Risk factors for SSI were determined using multivariate logistic regression analysis. We analyzed microbiological and related treatment data for different SSI types.
resultsAmong 2061 patients who underwent craniotomy for brain tumor, 31 had SSI (1.50%). In the multivariate logistic regression analysis, body mass index (BMI) and operative duration were identified as independent risk factors for SSI. The most common microorganism isolated from SSIs was Staphylococcus epidermidis (22.9%), and drug sensitivity results showed that gram-positive bacteria were sensitive to linezolid, vancomycin and tigecycline, whereas gram-negative bacteria were sensitive to meropenem, cefepime and ceftazidime. Six of the seven patients who underwent bone flap removal due to osteomyelitis were infected with gram-negative bacteria.
conclusionsBMI and operative duration were identified as independent risk factors for SSI. Diabetes mellitus, previous ratio therapy, type of incision, recurrence tumor and other risk factors were not found to be associated with the occurrence of SSI in this study.
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