Evidence map›Paper›PMID 37553651›Full record

ArticleBMC infectious diseases2023

ABO, Lewis blood group systems and secretory status with H.pylori infection in yemeni dyspeptic patients: a cross- sectional study.

Mohammed Abdulwahid Almorish, Boshra Al-Absi, Ahmed M E Elkhalifa, Elham Elamin, Abozer Y Elderdery, Abdulaziz H Alhamidi

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. The Prevalence ofMedicina (Kaunas, Lithuania) · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Mohammed Abdulwahid AlmorishDepartment of Hematology, Faculty of Medicine and Health Sciences, Sana'a University, Sana'a, Yemen. m.almorish@su.edu.ye.ORCID http://orcid.org/0000-0001-5296-7115
Boshra Al-AbsiDepartment of Hematology, Faculty of Medicine and Health Sciences, Sana'a University, Sana'a, Yemen.
Ahmed M E ElkhalifaPublic Heath Department, College of Health Sciences, Saudi Electronic University, Riyadh, Saudi Arabia.ORCID http://orcid.org/0000-0003-0549-249X
Elham ElaminDepartment of Hematology, Faculty of Medical Laboratory Sciences, University of El Imam El Mahdi, Kosti, 1158, Sudan.
Abozer Y ElderderyDepartment of Clinical Laboratory Sciences, College of Applied Medical Science, Jouf University, Sakaka, Saudi Arabia.
Abdulaziz H AlhamidiClinical Laboratory Sciences Department, College of Applied Medical Science, King Saud University, Riyadh, Saudi Arabia.
Sana'a University · YEJouf University · SAKing Saud University · SASaudi Electronic University · SAUniversity of El Imam El Mahdi · SD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ABO and Lewis blood group antigens are potential factors in susceptibility to H. pylori infection. This research aimed to examine the prevalence of Helicobater pylori (H.pylori) infection and its association with ABO, Lewis blood group systems, and secretory status in Yemeni symptomatic patients.

methodsIn a cross-sectional study, 103 patients referred for endoscopy due to dyspepsia were included. H pylori infection was assessed using stool antigen and serum antibody rapid tests. ABO and Lewis blood group systems were examined using hemagglutination assay. Saliva samples were investigated for identification of the secretory phenotype using hemagglutination inhibition test.

resultsThe prevalence of H. pylori infection was (80.6%), with a higher rate of infection in females than males. The ABO blood groups were found to be significantly different between males and females (p = 0.047). The O blood group was prevalent among H. pylori patients, especially secretors. There was a significant association between ABO blood groups and H. pylori infection (p = 0.001). The Le (a + b+) phenotype was the most common, followed by Le (a + b-), Le (a-b+), and Le (a-b-). Lewis blood group systems and secretory status of symptomatic patients were not associated with H. pylori infection. The results showed that serum Ab test for H. pylori achieved poor sensitivity (68%), specificity of 55%; positive predictive value (PPV) 86%, negative predictive value (NPV) 29% and accuracy 65.1%.

conclusionThe prevalence of H. pylori infection was high in Yemeni patients. This infection was linked to the O and Le (a + b+) secretor phenotype. The H. pylori stool Ag test is the most reliable noninvasive diagnostic method for detecting H. pylori infection.

Indexed as

DyspepsiaHelicobacter InfectionsHelicobacter pyloriABO Blood-Group SystemCross-Sectional StudiesFemaleHumansLewis Blood Group AntigensMalePhenotypeABO Blood-Group SystemLewis Blood Group AntigensABOH.pyloriLeLewisSecretor

Identifiers

PMID37553651
PMCPMC10408178
OpenAlexW4385659332

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.