Evidence map›Paper›PMID 37553502›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2023

Improved patient-reported outcomes after open preperitoneal inguinal hernia repair compared to anterior Lichtenstein repair: 10-year ACHQC analysis.

Divyansh Agarwal, Tina Bharani, Nora Fullington, Lauren Ott, Molly Olson, Benjamin Poulose, Jeremy Warren, Michael Reinhorn

Open access · hybridAbstract read
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Ambulatory bilateral groin hernia repair: open preperitoneal versus laparoscopic outcomes.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  5. Review
  6. Review
  7. Article
  8. Open vs. robot-assisted preperitoneal inguinal hernia repair. Are they truly clinically different?Hernia : the journal of hernias and abdominal wall surgery · 2024
    Article
  9. Article
  10. A Call to Change the Nomenclature of "Open" Inguinal Hernia Repair.Journal of abdominal wall surgery : JAWS · 2024
    Article
  11. Delivering what inguinal hernia patients really really want.Hernia : the journal of hernias and abdominal wall surgery · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Divyansh AgarwalDepartment of Surgery, Massachusetts General Hospital, 55 Fruit St., GRB 425, Boston, MA, 02114, USA. dagarwal@mgh.harvard.edu.ORCID http://orcid.org/0000-0003-0404-6877
Tina BharaniBrigham and Women's Hospital, Department of Surgery, Boston, MA, USA.
Nora FullingtonBoston Hernia and Pilonidal Center, 20 Walnut Street, Suite 100, Wellesley, MA, 02481, USA.
Lauren OttBoston Hernia and Pilonidal Center, 20 Walnut Street, Suite 100, Wellesley, MA, 02481, USA.
Molly OlsonDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Benjamin PouloseCenter for Abdominal Core Health, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Jeremy WarrenDepartment of Surgery, Division of Minimal Access, and Bariatric Surgery, Prisma Health Upstate, 701 Grove Rd, ST 3, Greenville, SC, 29605, USA.
Michael ReinhornBoston Hernia and Pilonidal Center, 20 Walnut Street, Suite 100, Wellesley, MA, 02481, USA. mreinhorn@bostonhernia.com.
Newton Wellesley Hospital · USBrigham and Women's Hospital · USCornell University · USMassachusetts General Hospital · USPrisma Health · USThe Ohio State University Wexner Medical Center · USTufts University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe Lichtenstein repair has been synonymous with "open" inguinal hernia repair (IHR) for 40 years. However, international guidelines have suggested that posterior mesh placement results in advantageous biomechanics and reduced risk of nerve-related chronic pain. Additionally, the use of local anesthetics has been shown to reduce postoperative pain and complication risks. An open transrectus preperitoneal/open preperitoneal (TREPP/OPP) repair combines posterior mesh placement with the use of local anesthetic and as such could be the ideal repair for primary inguinal hernia. Using the Abdominal Core Health Quality Collaborative (ACHQC) registry, we compared open anterior mesh with open posterior mesh repairs.

methodsWe performed a propensity score matched analysis of patients undergoing open IHR between 2012 and 2022 in the ACHQC. After 1:1 optimal matching, both the TREPP/OPP and Lichtenstein cohorts were balanced with 451 participants in each group. Outcomes included patient-reported quality of life (QoL), hernia recurrence, and postoperative opioid use.

resultsImprovement was seen after TREPP/OPP in EuraHS QoL score at 30 days (OR 0.558 [0.408, 0.761]; p = 0.001), and the difference persisted at 1 year (OR 0.588 [0.346, 0.994]; p = 0.047). Patient-reported opioid use at 30-day follow-up was significantly lower in the TREPP/OPP cohort (OR 0.31 [0.20, 0.48]; p < 0.001). 30-day frequency of surgical-site occurrences was significantly higher in the Lichtenstein repair cohort (OR 0.22 [0.06-0.61]; p = 0.007). There were no statistically significant differences in hernia recurrence risk at 1 year, or rates of postoperative bleeding, peripheral nerve injury, DVTs, or UTIs.

conclusionOur analysis demonstrates a benefit of posterior mesh placement (TREPP/OPP) over anterior mesh placement (Lichtenstein) in open inguinal hernia repair in patient-reported QoL and reduced opioid use.

Indexed as

Hernia, InguinalAnalgesics, OpioidHerniorrhaphyHumansQuality of LifeSurgical MeshAnalgesics, OpioidInguinal herniaLichtensteinPreperitoneal repairQuality-of-lifeTREPP/OPP

Identifiers

PMID37553502
PMCPMC10533599
OpenAlexW4385655543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.