Evidence map›Paper›PMID 37553256›Full record

ArticleCanadian journal of surgery. Journal canadien de chirurgie

A prospective Canadian gastroesophageal cancer database: What have we learned?

Kieran Purich, Daniel Skubleny, Sunita Ghosh, Eric L R Bédard, Kenneth C Stewart, Scott T Johnson, Erika Haase, Michael McCall, Dan Schiller

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian journal of surgery. Journal canadien de chirurgie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kieran PurichFrom the Department of Surgery, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Bédard, Stewart, Johnson, Haase, McCall, Schiller); the Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Ghosh, Bédard, Stewart, Johnson, Haase, McCall, Schiller); and the Department of Oncology, University of Alberta, Edmonton, Alta. (Ghosh) kpurich@ualberta.ca.
Daniel SkublenyFrom the Department of Surgery, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Bédard, Stewart, Johnson, Haase, McCall, Schiller); the Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Ghosh, Bédard, Stewart, Johnson, Haase, McCall, Schiller); and the Department of Oncology, University of Alberta, Edmonton, Alta. (Ghosh).
Sunita GhoshFrom the Department of Surgery, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Bédard, Stewart, Johnson, Haase, McCall, Schiller); the Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Ghosh, Bédard, Stewart, Johnson, Haase, McCall, Schiller); and the Department of Oncology, University of Alberta, Edmonton, Alta. (Ghosh).
Eric L R BédardFrom the Department of Surgery, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Bédard, Stewart, Johnson, Haase, McCall, Schiller); the Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Ghosh, Bédard, Stewart, Johnson, Haase, McCall, Schiller); and the Department of Oncology, University of Alberta, Edmonton, Alta. (Ghosh).
Kenneth C StewartFrom the Department of Surgery, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Bédard, Stewart, Johnson, Haase, McCall, Schiller); the Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Ghosh, Bédard, Stewart, Johnson, Haase, McCall, Schiller); and the Department of Oncology, University of Alberta, Edmonton, Alta. (Ghosh).
Scott T JohnsonFrom the Department of Surgery, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Bédard, Stewart, Johnson, Haase, McCall, Schiller); the Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Ghosh, Bédard, Stewart, Johnson, Haase, McCall, Schiller); and the Department of Oncology, University of Alberta, Edmonton, Alta. (Ghosh).
Erika HaaseFrom the Department of Surgery, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Bédard, Stewart, Johnson, Haase, McCall, Schiller); the Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Ghosh, Bédard, Stewart, Johnson, Haase, McCall, Schiller); and the Department of Oncology, University of Alberta, Edmonton, Alta. (Ghosh).
Michael McCallFrom the Department of Surgery, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Bédard, Stewart, Johnson, Haase, McCall, Schiller); the Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Ghosh, Bédard, Stewart, Johnson, Haase, McCall, Schiller); and the Department of Oncology, University of Alberta, Edmonton, Alta. (Ghosh).
Dan SchillerFrom the Department of Surgery, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Bédard, Stewart, Johnson, Haase, McCall, Schiller); the Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta. (Purich, Skubleny, Ghosh, Bédard, Stewart, Johnson, Haase, McCall, Schiller); and the Department of Oncology, University of Alberta, Edmonton, Alta. (Ghosh).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMinimal literature exists on outcomes for Canadian patients with gastroesophageal adenocarcinoma (GEA). The objective of our study was to establish a prospective clinical database to evaluate demographic characteristics, presentation and outcomes of patients with GEA.

methodsPatients diagnosed with GEA were recruited from Jan. 30, 2017, to Aug. 30, 2020. Data collected included demographic characteristics, presentation, treatment and survival. A multivariable model for overall survival in patients treated with curative intent was created using sex, lymph node status, resection margin status, age and tumour location as variables.

resultsA total of 122 patients with adenocarcinoma of the stomach or gastroesophageal junction were included. Median age was 65 years (interquartile range [IQR] 59-74), 70% of patients were male and 26% were born outside of Canada. Median follow-up time was 14.5 (IQR 8.0-31.0) months. Following staging computed tomography scanning, 88% of patients were deemed to have potentially resectable disease. Eighty-one (76%) received staging laparoscopy and 74 (61%) were treated with curativeintent surgery. Forty-six (62%) patients had nodal metastases. The median number of nodes harvested was 22 (IQR 18-30). The R0 resection margin rate was 82%. The 3-year overall survival for patients who received curative-intent treatment was 63% and 38% for all patients. On multivariable analysis, female sex (hazard ratio [HR] 3.88,

conclusionMany of the patients with GEA in this study presented with advanced disease, and only 61% were offered curative-intent surgery. A prospective multicentre national GEA database is now being established.

Indexed as

AdenocarcinomaEsophageal NeoplasmsStomach NeoplasmsAgedCanadaEsophagogastric JunctionFemaleHumansMaleMargins of ExcisionNeoplasm StagingPrognosisProspective StudiesRetrospective StudiesSurvival Rate

Identifiers

PMID37553256
PMCPMC10414783

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.