Evidence map›Paper›PMID 37553217›Full record

ArticleRespiratory care2023

Associations With Severe Desaturation Events Among Children Receiving Noninvasive Respiratory Support at Time of Intubation.

Jamie M Furlong-Dillard, Anh Nguyen, Michael D Facciolo, Yana B Feygin, Natalie Napolitano, Guillaume Emeriaud, John W Berkenbosch, Erin B Owen

Abstract read
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In one paragraph

Article in Respiratory care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Jamie M Furlong-DillardDivision of Pediatric Critical Care, Department of Pediatrics, Norton Children's Hospital, University of Louisville School of Medicine, Louisville, Kentucky. jamie.furlong-dillard@louisville.edu.
Anh NguyenDivision of Pediatric Critical Care, Department of Pediatrics, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, Washington.
Michael D FaccioloDivision of Pediatric Critical Care, Department of Pediatrics, Norton Children's Hospital, University of Louisville School of Medicine, Louisville, Kentucky.
Yana B FeyginNorton Children's Research Institute affiliated with the University of Louisville School of Medicine, Louisville, Kentucky.
Natalie NapolitanoRespiratory Care Department, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Guillaume EmeriaudDivision des Soins Intensifs Pédiatriques, Département de Pédiatrie, CHU Sainte-Justine, Université de Montréal, Montréal, Québec, Canada.
John W BerkenboschDivision of Pediatric Critical Care, Department of Pediatrics, Norton Children's Hospital, University of Louisville School of Medicine, Louisville, Kentucky.
Erin B OwenDivision of Pediatric Critical Care, Department of Pediatrics, Norton Children's Hospital, University of Louisville School of Medicine, Louisville, Kentucky.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndotracheal intubation is a common procedure associated with adverse events, including severe desaturation. Many patients receive noninvasive respiratory support to reduce the need for intubation. There are minimal data about the association between noninvasive respiratory support and the risk of a severe desaturation event during intubation. We aim to differentiate patients based on the level of noninvasive respiratory support, analyze the severe desaturation event by groups, and identify modifiable risk factors.

methodsOral intubations, excluding tube exchanges or re-intubation after unplanned extubation, from October 2018 through July 2020, at the study site were reviewed. A severe desaturation event was defined as [Formula: see text] < 70% or a >15% decrease from baseline in cyanotic heart disease. We analyzed outcomes by 4 groups: room air/nasal cannula (≤0.5 L/kg/min), high-flow nasal cannula (HFNC) (0.5-2 L/kg/min), high HFNC (≥2 L/kg/min), and noninvasive ventilation (NIV).

resultsOf 243 subjects who were intubated, 31% were receiving room air/nasal cannula, 25% were receiving HFNC, 18% were receiving high HFNC, and 26% were receiving NIV. Twelve percent of all the subjects had a severe desaturation event. In a univariate analysis, the incidence of a severe desaturation event was similar among all levels of respiratory support (

conclusionsResults of our study suggest that [Formula: see text] > 0.60, the duration of noninvasive respiratory support, and exposure to NIV before an intubation are risk factors of severe desaturation events during intubation.

Indexed as

Noninvasive VentilationRespiratory InsufficiencyCannulaChildHumansIntensive Care UnitsIntubation, IntratrachealOxygen Inhalation TherapyRespiration, Artificialhigh flow nasal cannulaintubationnon-invasive respiratory supportnon-invasive ventilationsevere desaturation

Identifiers

PMID37553217
PMCPMC10676262

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.