Evidence map›Paper›PMID 37552757›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Natural selection has driven the recurrent loss of an immunity gene that protects

Ramesh Arunkumar, Shuyu Olivia Zhou, Jonathan P Day, Sherifat Bakare, Simone Pitton, Yexin Zhang, Chi-Yun Hsing, Sinead O'Boyle, Juan Pascual-Gil, Belinda Clark and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 4 countries.

Ramesh Arunkumar *Department of Genetics, School of Biological Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom.ORCID 0000-0003-0050-3516
Shuyu Olivia Zhou *Department of Genetics, School of Biological Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom.
Jonathan P Day *Department of Genetics, School of Biological Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom.
Sherifat BakareDepartment of Genetics, School of Biological Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom.
Simone PittonDepartment of Genetics, School of Biological Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom.ORCID 0000-0002-0939-9308
Yexin ZhangDepartment of Genetics, School of Biological Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom.ORCID 0000-0001-8253-4951
Chi-Yun HsingDepartment of Genetics, School of Biological Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom.
Sinead O'BoyleDepartment of Genetics, School of Biological Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom.ORCID 0009-0008-7905-7400
Juan Pascual-GilDepartment of Genetics, School of Biological Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom.ORCID 0009-0005-9974-6893
Belinda ClarkDepartment of Genetics, School of Biological Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom.ORCID 0009-0009-9040-8766
Rachael J ChandlerDepartment of Genetics, School of Biological Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom.
Alexandre B LeitãoDepartment of Genetics, School of Biological Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom.ORCID 0000-0001-9004-1831
Francis M JigginsDepartment of Genetics, School of Biological Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom.ORCID 0000-0001-7470-8157
University of Cambridge · GBUniversity College Dublin · IEUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymorphisms in immunity genes can have large effects on susceptibility to infection. To understand the origins of this variation, we have investigated the genetic basis of resistance to the parasitoid wasp

Indexed as

ParasitesWaspsAnimalsDrosophilaDrosophila melanogasterHost-Parasite InteractionsLectinsSelection, GeneticLectinscis-regulatory polymorphismC-type lectinLeptopilina boulardiloss of functionmelanization

Identifiers

PMID37552757
PMCPMC10438844
OpenAlexW4385655638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.