Evidence map›Paper›PMID 37552410›Full record

ArticleNeurocritical care2023

Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Neuroimaging.

Brian L Edlow, Varina L Boerwinkle, Jitka Annen, Melanie Boly, Olivia Gosseries, Steven Laureys, Pratik Mukherjee, Louis Puybasset, Robert D Stevens, Zachary D Threlkeld and 3 more

Erratum issuedOpen access · greenAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Neurocritical care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 5 countries.

Brian L Edlow *Center for Neurotechnology and Neurorecovery, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. bedlow@mgh.harvard.edu.ORCID 0000-0001-7235-8456
Varina L Boerwinkle *Clinical Resting-State Functional Magnetic Resonance Imaging Laboratory and Service, Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Jitka AnnenComa Science Group, GIGA Consciousness, University of Liège, Liège, Belgium.
Melanie BolyDepartment of Neurology, University of Wisconsin, Madison, WI, USA.
Olivia GosseriesComa Science Group, GIGA Consciousness, University of Liège, Liège, Belgium.
Steven LaureysComa Science Group, GIGA Consciousness, University of Liège, Liège, Belgium.
Pratik MukherjeeDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA.
Louis PuybassetDepartment of Anesthesiology and Intensive Care, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Paris, France.
Robert D StevensDepartments of Anesthesiology and Critical Care Medicine, Neurology, Radiology, and Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Zachary D ThrelkeldDepartment of Neurology, Stanford University School of Medicine, Stanford, CA, USA.
Virginia F J Newcombe *PACE Section, Department of Medicine, University of Cambridge, Cambridge, UK.
Davinia Fernandez-Espejo *School of Psychology and Centre for Human Brain Health, University of Birmingham, Birmingham, UK.
The Curing Coma Campaign and its Contributing Members
University of Liège · BEBoston University · USUniversity of California, San Francisco · USUniversity of North Carolina at Chapel Hill · USJohns Hopkins University · USSorbonne Université · FRStanford University · USUniversity of Birmingham · GBUniversity of Cambridge · GBUniversity of Wisconsin–Madison · US

Funding

MicroRNA Endotypes of Systemic Inflammation in Sub-Arachnoid hemorrhaGE (MESSAGE)R21NS113037 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHOU, SHERRY HSIANG-YI · 2019 to 2019
$390k
NINDS NIH HHS R21NS113037
6 · The paper itself

Abstract

backgroundOver the past 5 decades, advances in neuroimaging have yielded insights into the pathophysiologic mechanisms that cause disorders of consciousness (DoC) in patients with severe brain injuries. Structural, functional, metabolic, and perfusion imaging studies have revealed specific neuroanatomic regions, such as the brainstem tegmentum, thalamus, posterior cingulate cortex, medial prefrontal cortex, and occipital cortex, where lesions correlate with the current or future state of consciousness. Advanced imaging modalities, such as diffusion tensor imaging, resting-state functional magnetic resonance imaging (fMRI), and task-based fMRI, have been used to improve the accuracy of diagnosis and long-term prognosis, culminating in the endorsement of fMRI for the clinical evaluation of patients with DoC in the 2018 US (task-based fMRI) and 2020 European (task-based and resting-state fMRI) guidelines. As diverse neuroimaging techniques are increasingly used for patients with DoC in research and clinical settings, the need for a standardized approach to reporting results is clear. The success of future multicenter collaborations and international trials fundamentally depends on the implementation of a shared nomenclature and infrastructure.

methodsTo address this need, the Neurocritical Care Society's Curing Coma Campaign convened an international panel of DoC neuroimaging experts to propose common data elements (CDEs) for data collection and reporting in this field.

resultsWe report the recommendations of this CDE development panel and disseminate CDEs to be used in neuroimaging studies of patients with DoC.

conclusionsThese CDEs will support progress in the field of DoC neuroimaging and facilitate international collaboration.

Indexed as

ConsciousnessDiffusion Tensor ImagingCommon Data ElementsConsciousness DisordersHumansMagnetic Resonance ImagingNeuroimagingComaCommon data elementsConsciousnessNeuroimaging

Identifiers

PMID37552410
OpenAlexW4385665364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.