Evidence map›Paper›PMID 37552381›Full record

ReviewCardiovascular drugs and therapy2024

Direct Oral Anticoagulants: Navigating Through Clinical Challenges.

Maria Ioannou, Elena Leonidou, Ioanna Chaziri, Angeliki Mouzarou

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cardiovascular drugs and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria IoannouDepartment of Cardiology, General Hospital Limassol, State Health Organization Services, 4131, Limassol, Cyprus. mar.ioannou25@gmail.com.ORCID 0000-0001-6230-7137
Elena LeonidouDepartment of Cardiology, General Hospital Limassol, State Health Organization Services, 4131, Limassol, Cyprus.ORCID 0000-0001-6349-9214
Ioanna ChaziriDepartment of Pneumonology, Northern Älvborg County Hospital, Trollhättan, Sweden.ORCID 0000-0002-2934-7871
Angeliki MouzarouDepartment of Cardiology, General Hospital Paphos, State Health Organization Services, Paphos, Cyprus.ORCID 0000-0002-6687-5075

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDirect oral anticoagulants (DOACs) have been approved, for over a decade, by both European and American medicine agencies, for treatment and prevention of several cardiovascular conditions. Since then, an increasing amount of data has been added to the medical literature day by day, resulting in a dichotomy in selection of the appropriate agent, dosage, and duration of treatment for special populations with multiple comorbidities. Considering these issues, we have prepared a comprehensive review for the clinical practitioner, to optimize the DOAC utilization in clinical practice.

methodsA thorough literature search and review was conducted, concerning mainly the last decade. Our review focused on the current guidelines and the most recently published studies in PubMed, Science Direct Scopus, and Google Scholar to date.

conclusionThe purpose of this study is to provide guidance for healthcare professionals for making proper decisions when confronted with clinical challenges. Nevertheless, further research is required to establish DOAC superiority in complicated cases, where there is clinical uncertainty.

Indexed as

AnticoagulantsAdministration, OralBlood CoagulationCardiovascular DiseasesFactor Xa InhibitorsHemorrhageHumansPractice Guidelines as TopicAnticoagulantsFactor Xa InhibitorsClinical ChallengesComorbiditiesDOACsIndications

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.