Evidence map›Paper›PMID 37552296›Full record

ReviewPflugers Archiv : European journal of physiology2023

Measured GFR in murine animal models: review on methods, techniques, and procedures.

Silvia Teixido-Trujillo, Sergio Luis-Lima, Marina López-Martínez, Maruja Navarro-Díaz, Laura Díaz-Martín, Elia Escasany-Martínez, Flavio Gaspari, Ana Elena Rodríguez-Rodríguez

Abstract readReview
In one paragraph

Review in Pflugers Archiv : European journal of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. High frailty index scores predict mortality and changes in blood-based biomarkers in aging female mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  2. Glomerular filtration by the kidney nearly arrests during torpor and is rapidly restored as hibernating ground squirrels begin to arouse.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Silvia Teixido-TrujilloUniversidad de La Laguna, Faculty of Medicine, San Cristóbal de La Laguna, Spain.
Sergio Luis-LimaDepartment of Laboratory Medicine, Complejo Hospitalario Universitario de Canarias, San Cristóbal de La Laguna, Spain.
Marina López-MartínezDepartment of Nephology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Maruja Navarro-DíazDepartment of Nephology, Hospital de Sant Joan Despí Moisès Broggi, Barcelona, Spain.
Laura Díaz-MartínResearch Unit, Hospital Universitario de Canarias, San Cristóbal de La Laguna, Spain.
Elia Escasany-MartínezLipobeta group. Departamento de Ciencias Básicas de la Salud, Facultad de Ciencias de la Salud, Universidad Rey Juan Carlos, Madrid, Spain.
Flavio GaspariInstituto di Ricerche Farmacologiche Mario Negri (IRCCS), Clinical Research Center for Rare Diseases 'Aldo & Cele Daccò, Bergamo, Italy.
Ana Elena Rodríguez-RodríguezUniversidad de La Laguna, Faculty of Medicine, San Cristóbal de La Laguna, Spain. anarrguez@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic kidney disease (CKD) is one of the most common chronic diseases worldwide, with increasing rates of morbidity and mortality. Thus, early detection is essential to prevent severe adverse events and the progression of kidney disease to an end stage. Glomerular filtration rate (GFR) is the most appropriate index to evaluate renal function in both clinical practice and basic medical research. Several animal models have been developed to understand renal disease induction and progression. Specifically, murine models are useful to study the pathogenesis of renal damage, so a reliable determination of GFR is essential to evaluate the progression of CKD. However, as in clinical practise, the estimation of GFR in murine by levels of serum/urine creatinine or cystatin-C could not be accurate and needed other more reliable methods. As an alternative, the measurement of GFR by the clearance of exogenous markers like inulin, sinistrin,

Indexed as

Glomerular Filtration RateRenal Insufficiency, ChronicAnimalsBiomarkersDisease Models, AnimalKidneyMiceBiomarkersAnimal modelsExogenous markersGlomerular filtration rate (GFR)Kidney damageRenal function

Identifiers

PMID37552296
PMCPMC10567863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.