Evidence map›Paper›PMID 37551613›Full record

ArticlePharmacogenomics2023

Pharmacogenomic variation in the Malagasy population: implications for the antimalarial drug primaquine metabolism.

Estee Y Cramer, Jacquelaine Bartlett, Ernest R Chan, Andrea Gaedigk, Arsene C Ratsimbasoa, Rajeev K Mehlotra, Scott M Williams, Peter A Zimmerman

Open access · hybridAbstract read
In one paragraph

Article in Pharmacogenomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Estee Y CramerCenter for Global Health & Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.ORCID 0000-0003-1373-3177
Jacquelaine BartlettPopulation & Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Ernest R ChanPopulation & Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Andrea GaedigkDivision of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy Research Institute (CMRI), Kansas City, MO 64108, USA.ORCID 0000-0001-6968-1893
Arsene C RatsimbasoaUniversity of Fianarantsoa, Fianarantsoa, Madagascar.
Rajeev K MehlotraCenter for Global Health & Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.ORCID 0000-0003-4205-750X
Scott M WilliamsPopulation & Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.ORCID 0000-0002-4835-9544
Peter A ZimmermanCenter for Global Health & Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.ORCID 0000-0002-5349-4513
Case Western Reserve University · USCenter for Global Health · USMercy Research · USUniversité de Fianarantsoa · MGUniversity of Massachusetts Amherst · US

Funding

Madagascar P. vivax Invasion of Duffy-negative Red CellsR01AI097366 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI ZIMMERMAN, PETER A. · 2013 to 2017
$3.6M
Primaquine metabolism and treatment of P. vivax in MadagascarR01AI148469 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI WILLIAMS, SCOTT MATTHEW, ZIMMERMAN, PETER A. · 2020 to 2023
$2.6M
NIAID NIH HHS R01 AI097366NIAID NIH HHS R01 AI148469
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AntimalarialsChloroquineDNA Copy Number VariationsGenome-Wide Association StudyHumansPharmacogeneticsPrimaquineAntimalarialsChloroquinePrimaquinecopy number variationgenome-wide arrayMadagascarmalaria treatmentPlasmodium vivaxprimaquine

Identifiers

PMID37551613
PMCPMC10621762
OpenAlexW4385659870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.