Evidence map›Paper›PMID 37551219›Full record

ArticleCureus2023

Sotrovimab Treatment for COVID-19 Effective in a B-Cell-Depleted Patient After Anti-CD20 Treatment.

Kazuyuki Murase, Kohichi Takada, Yohei Arihara, Koji Miyanishi, Junji Kato

Abstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kazuyuki MuraseDepartment of Medical Oncology, Sapporo Medical University, Sapporo, JPN.
Kohichi TakadaDepartment of Medical Oncology, Sapporo Medical University, Sapporo, JPN.
Yohei AriharaDepartment of Medical Oncology, Sapporo Medical University, Sapporo, JPN.
Koji MiyanishiDepartment of Medical Oncology, Sapporo Medical University, Sapporo, JPN.
Junji KatoDepartment of Medical Oncology, Sapporo Kiyota Hospital, Sapporo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with hematologic malignancies are well known to have prolonged COVID-19 pneumonia. The cause has been reported to be B cell depletion after administration of anti-CD20 antibodies. Here, we report a case of COVID-19 pneumonia due to prolonged B-cell depletion after anti-CD20 antibody therapy for malignant lymphoma two years before. Sotrovimab, a neutralizing antibody that was designed to prevent the progression of COVID-19, was successful in preventing the progression to severe disease in this B-cell-depleted patient.

Indexed as

anti-cd20 treatmentb cell depletioncovid-19hematologic malignancysotrovimab

Identifiers

PMID37551219
PMCPMC10404336

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.