Evidence map›Paper›PMID 37551167›Full record

ArticleAsian biomedicine : research, reviews and news2022

Promoter methylation analysis of

Xian Zhang, Aihua Li, Jie Wu, Yu Wu, Xiaoping Ma, Yanjun Liu, Qingfa Chen, Yan Zhang

Abstract read
In one paragraph

Article in Asian biomedicine : research, reviews and news, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xian ZhangDepartment of Gynecology and Obstetrics, Liaocheng People's Hospital and Liaocheng Clinical School of Shandong First Medical University, Liaocheng, Shandong 252000, China.ORCID https://orcid.org/0000-0002-9922-3460
Aihua LiDepartment of Gynecology and Obstetrics, Liaocheng People's Hospital and Liaocheng Clinical School of Shandong First Medical University, Liaocheng, Shandong 252000, China.ORCID https://orcid.org/0000-0002-0251-7308
Jie WuDepartment of Pathology, Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China.ORCID https://orcid.org/0000-0002-5445-4185
Yu WuDepartment of Gynecology and Obstetrics, Liaocheng People's Hospital and Liaocheng Clinical School of Shandong First Medical University, Liaocheng, Shandong 252000, China.ORCID https://orcid.org/0000-0002-9964-4898
Xiaoping MaDepartment of Gynecology and Obstetrics, Liaocheng People's Hospital and Liaocheng Clinical School of Shandong First Medical University, Liaocheng, Shandong 252000, China.ORCID https://orcid.org/0000-0003-3202-2514
Yanjun LiuDepartment of Gynecology and Obstetrics, Liaocheng People's Hospital and Liaocheng Clinical School of Shandong First Medical University, Liaocheng, Shandong 252000, China.ORCID https://orcid.org/0000-0003-4565-3147
Qingfa ChenInstitute of Tissue Engineering and Regenerative Medicine, Liaocheng People's Hospital and Liaocheng Clinical School of Shandong First Medical University, Liaocheng, Shandong 252000, China.ORCID https://orcid.org/0000-0002-3502-0234
Yan ZhangDepartment of Gynecology and Obstetrics, Liaocheng People's Hospital and Liaocheng Clinical School of Shandong First Medical University, Liaocheng, Shandong 252000, China.ORCID https://orcid.org/0000-0001-9711-006X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dickkopf 2 ( Objectives: To investigate the expression and promoter methylation levels of Methods: We used the Gene Expression Omnibus, Oncomine, Cancer Genome Atlas, and University of ALabama at Birmingham CANcer data analysis databases, reverse transcription-PCR, and methylation-specific PCR analysis to predict and examine the expression of DKK2 mRNA and Results: DKK2 mRNA expression was downregulated in all cancer cell lines and cervical cancer tissues, whereas hypermethylation of Conclusions:

Indexed as

biomarkersdata miningDKK2 proteinDNA methylationhumanhuman papillomavirusuterine cervical neoplasms

Identifiers

PMID37551167
PMCPMC10321177

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.