Evidence map›Paper›PMID 37551100›Full record

ArticleCanadian journal of psychiatry. Revue canadienne de psychiatrie2023

Does the Ranking Matter? A Retrospective Cohort Study Investigating the Impact of the

Fabiano A Gomes, Henrique Dumay, Julia Fagen, Natalie Palma, Roumen Milev, Elisa Brietzke

Registry-linked trialAbstract read
In one paragraph

Article in Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07213492 (A Bridge to Better Days), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07213492 narecruitingnot on this mapstarted 2026, after this paper: background citation

A Bridge to Better Days: A Pilot Study of a Multimodal Intervention to Support the Successful Transition From Hospital to Community Care for People Living With Bipolar Disorder

TypeinterventionalSponsorMcMaster UniversityRan2026 to 2027Enrolled10ConditionsBipolar Disorder (BD), PsychosisArmsGroup-Based Psychoeducation, Peer Support, Personalized Support for Community Healthcare Provider
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fabiano A GomesDepartment of Psychiatry, Queen's University, Kingston, ON, Canada.ORCID 0000-0002-7690-1580
Henrique DumayUniversity of Brasilia, Brasilia, Brazil.ORCID 0000-0001-9328-4441
Julia FagenDepartment of Psychiatry, Queen's University, Kingston, ON, Canada.
Natalie PalmaDepartment of Psychiatry, Queen's University, Kingston, ON, Canada.
Roumen MilevDepartment of Psychiatry, Queen's University, Kingston, ON, Canada.ORCID 0000-0001-6884-171X
Elisa BrietzkeDepartment of Psychiatry, Queen's University, Kingston, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThere is limited data about the impact of mood disorders treatment guidelines on clinical outcomes. The objective of this study was to investigate the impact of prescribers' adherence to the 2018 Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) treatment guidelines recommendations on the readmission rates of patients hospitalized for mania.

methodA retrospective cohort of all individuals admitted due to acute mania to Kingston General Hospital, Kingston, ON, from January 2018 to July 2021 was included in this study. Patient variables and data regarding index admission and subsequent hospitalizations were extracted from medical records up to December 31, 2021. Treatment regimens were classified as first-line, second-line, noncompliant, or no treatment. We explored the associations between treatment regimens and the risk of readmissions using univariate, multivariate, and survival analysis.

resultsWe identified 211 hospitalizations related to 165 patients. The mean time-to-readmission was 211.8 days (standard deviation [SD]  =  247.1); the 30-day rehospitalization rate was 13.7%, and any rehospitalization rate was 40.3%. Compared to no treatment, only first-line treatments were associated with a statistically significant decreased risk of 30-day readmission (odds ratio [OR] = 0.209; 95% CI, 0.058 to 0.670). The risk of any readmission was reduced by first-line (OR = 0.387; 95% CI, 0.173 to 0.848) and noncompliant regimens (OR = 0.414; 95% CI, 0.174 to 0.982) compared to no treatment. On survival analysis, no treatment group was associated with shorter time-to-readmission (log-rank test,

conclusionsTreatment with first-line medications was associated with lower 30-day rehospitalization rates and longer time-to-readmission. Physicians' adherence to treatments with higher-ranked evidence for efficacy, safety, and tolerability may improve bipolar disorder outcomes.

Indexed as

Bipolar DisorderAnxietyCanadaHumansManiaPatient ReadmissionRetrospective Studiesbipolar disorderCANMATclinical guidelinesISBDmaniarehospitalization

Identifiers

PMID37551100
PMCPMC10411363

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.