Evidence map›Paper›PMID 37550912›Full record

ReviewCurrent medicinal chemistry2024

Non-oxidative Modified Low-density Lipoproteins: The Underappreciated Risk Factors for Atherosclerosis.

Yimeng Zhao, Qian Xu, Naiqi He, Mulin Jiang, Yingzhuo Chen, Zhong Ren, Zhihan Tang, Chunyan Wu, Lushan Liu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Non-oxidativeCurrent medicinal chemistry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yimeng ZhaoKey Laboratory for Arteriosclerology of Hunan Province, Department of Cardiovascular Medicine, Institute of Cardiovascular Disease, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, The Third Affiliated Hospital, Hengyang Medical College, University of South China, Hengyang 421001, China.
Qian XuKey Laboratory for Arteriosclerology of Hunan Province, Department of Cardiovascular Medicine, Institute of Cardiovascular Disease, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, The Third Affiliated Hospital, Hengyang Medical College, University of South China, Hengyang 421001, China.
Naiqi HeKey Laboratory for Arteriosclerology of Hunan Province, Department of Cardiovascular Medicine, Institute of Cardiovascular Disease, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, The Third Affiliated Hospital, Hengyang Medical College, University of South China, Hengyang 421001, China.
Mulin JiangKey Laboratory for Arteriosclerology of Hunan Province, Department of Cardiovascular Medicine, Institute of Cardiovascular Disease, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, The Third Affiliated Hospital, Hengyang Medical College, University of South China, Hengyang 421001, China.
Yingzhuo ChenKey Laboratory for Arteriosclerology of Hunan Province, Department of Cardiovascular Medicine, Institute of Cardiovascular Disease, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, The Third Affiliated Hospital, Hengyang Medical College, University of South China, Hengyang 421001, China.
Zhong RenKey Laboratory for Arteriosclerology of Hunan Province, Department of Cardiovascular Medicine, Institute of Cardiovascular Disease, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, The Third Affiliated Hospital, Hengyang Medical College, University of South China, Hengyang 421001, China.
Zhihan TangKey Laboratory for Arteriosclerology of Hunan Province, Department of Cardiovascular Medicine, Institute of Cardiovascular Disease, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, The Third Affiliated Hospital, Hengyang Medical College, University of South China, Hengyang 421001, China.
Chunyan WuKey Laboratory for Arteriosclerology of Hunan Province, Department of Cardiovascular Medicine, Institute of Cardiovascular Disease, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, The Third Affiliated Hospital, Hengyang Medical College, University of South China, Hengyang 421001, China.
Lushan LiuKey Laboratory for Arteriosclerology of Hunan Province, Department of Cardiovascular Medicine, Institute of Cardiovascular Disease, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, The Third Affiliated Hospital, Hengyang Medical College, University of South China, Hengyang 421001, China.

Funding

Hunan Provincial Innovation Foundation for Postgraduate QL20220217Natural Science Foundation of Hunan Province (2021JJ30596)
6 · The paper itself

Abstract

Atherosclerosis, the pathological basis of most cardiovascular diseases, is a main risk factor causing about 20 million deaths each year worldwide. Oxidized low-density lipoprotein is recognized as the most important and independent risk factor in initiating and promoting atherosclerosis. Numerous antioxidants are extensively used in clinical practice, but they have no significant effect on reducing the morbidity and mortality of cardiovascular diseases. This finding suggests that researchers should pay more attention to the important role of non-oxidative modified low-density lipoprotein in atherosclerosis with a focus on oxidized low-density lipoprotein. This review briefly summarizes several important non-oxidative modified low-density lipoproteins associated with atherosclerosis, introduces the pathways through which these non-oxidative modified low-density lipoproteins induce the development of atherosclerosis

Indexed as

AtherosclerosisLipoproteins, LDLAnimalsAntioxidantsHumansRisk FactorsAntioxidantsLipoproteins, LDLoxidized low density lipoproteinAtherosclerosiscarbamylated LDLglycated LDLlipoproteins.nitrated LDLnon-oxidative modified LDLs

Identifiers

PMID37550912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.