ReviewJournal of orthopaedic surgery and research2023
Fixators dynamization for delayed union and non-union of femur and tibial fractures: a review of techniques, timing and influence factors.
Review in Journal of orthopaedic surgery and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Instrumentalized 3D printed scaffolds enable bone regeneration and fracture healing monitoring in critical size bone defects.APL bioengineering · 2026Article
- Mechanical Intelligence in Bone Regeneration: Bridging Material and Cellular Memory for Enhanced Healing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Predictors of Delayed Union Following Locking Compression Plate Fixation of Tibial Shaft Fractures: A Prospective Observational Study.Journal of orthopaedic case reports · 2026Article
- Revisiting bone healing strategies: the potential of reverse dynamization in veterinary orthopedics.Frontiers in veterinary science · 2026Review
- Subject-specific multivariate modeling for regenerative rehabilitation of bone healing.APL bioengineering · 2025Article
- Predictive model of delayed union of tibial and fibular fractures based on PGC-1α, NOS, and Runx2.European journal of medical research · 2025Article
- Predictive value of nutritional status for delayed healing after open fracture of the extremities in the elderly: construction of a nomogram model.American journal of translational research · 2025Article
- Management of Distal Femoral Non-union: A Systematic Review.Indian journal of orthopaedics · 2024Review
- Comparative Study of Exchange Nailing and Augmentative Plating for Treating Aseptic Nonunion of Femoral Shafts Post Intramedullary Nailing: A Single-Blind, Multicentric Randomized Clinical Trial.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
The optimal balance between mechanical environment and biological factors is crucial for successful bone healing, as they synergistically affect bone development. Any imbalance between these factors can lead to impaired bone healing, resulting in delayed union or non-union. To address this bone healing disorder, clinicians have adopted a technique known as "dynamization" which involves modifying the stiffness properties of the fixator. This technique facilitates the establishment of a favorable mechanical and biological environment by changing a rigid fixator to a more flexible one that promotes bone healing. However, the dynamization of fixators is selective for certain types of non-union and can result in complications or failure to heal if applied to inappropriate non-unions. This review aims to summarize the indications for dynamization, as well as introduce a novel dynamic locking plate and various techniques for dynamization of fixators (intramedullary nails, steel plates, external fixators) in femur and tibial fractures. Additionally, Factors associated with the effectiveness of dynamization are explored in response to the variation in dynamization success rates seen in clinical studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.