Evidence map›Paper›PMID 37550730›Full record

ArticleTrials2023

The Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) for serious mental illness in community mental health part 2: study protocol for a hybrid type 2 effectiveness-implementation cluster-randomized trial using train-the-trainer.

Catherine A Callaway, Laurel D Sarfan, Emma R Agnew, Lu Dong, Julia M Spencer, Rafael Esteva Hache, Marlen Diaz, Shayna A Howlett, Krista R Fisher, Heather E Hilmoe Yates and 4 more

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05805657 (Implementing and Sustaining a Transdiagnostic Sleep and Circadian Treatment to Improve Severe Mental Illness Outcomes in Community Mental Health Part 2), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05805657 nacompletednot on this map

Implementing and Sustaining a Transdiagnostic Sleep and Circadian Treatment to Improve Severe Mental Illness Outcomes in Community Mental Health Part 2: Train-the-Trainer

TypeinterventionalSponsorUniversity of California, BerkeleyRan2020 to 2024Enrolled196ConditionsSleep Disorder, Circadian DysregulationArmsStandard Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C), Adapted Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C), Usual Care Delayed Treatment
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Catherine A Callaway *University of California, Berkeley, CA, USA.
Laurel D Sarfan *University of California, Berkeley, CA, USA.
Emma R AgnewUniversity of California, Berkeley, CA, USA.
Lu DongRAND Corporation, Santa Monica, CA, USA.
Julia M SpencerUniversity of California, Berkeley, CA, USA.
Rafael Esteva HacheUniversity of California, Berkeley, CA, USA.
Marlen DiazUniversity of California, Berkeley, CA, USA.
Shayna A HowlettUniversity of California, Berkeley, CA, USA.
Krista R FisherUniversity of California, Berkeley, CA, USA.
Heather E Hilmoe YatesUniversity of California, Berkeley, CA, USA.
Eric SticeStanford University, Stanford, CA, USA.
Amy M KilbourneUniversity of Michigan and VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Daniel J BuysseUniversity of Pittsburgh, Pittsburgh, PA, USA.
Allison G HarveyUniversity of California, Berkeley, CA, USA. aharvey@berkeley.edu.ORCID http://orcid.org/0000-0002-8609-0005

Funding

Implementing and Sustaining a Transdiagnostic Sleep and Circadian Treatment to Improve Severe Mental Illness Outcomes in Community Mental Health.R01MH120147 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARVEY, ALLISON G · 2019 to 2023
$3.9M
Advancing Sustainability of Evidence-Based Treatments in Community Mental HealthF32MH131284 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI SARFAN, LAUREL D · 2022 to 2024
$76k
NIMH NIH HHS F32 MH131284NIMH NIH HHS R01 MH120147
6 · The paper itself

Abstract

backgroundTrain-the-trainer (TTT) is a promising method for implementing evidence-based psychological treatments (EBPTs) in community mental health centers (CMHCs). In TTT, expert trainers train locally embedded individuals (i.e., Generation 1 providers) to deliver an EBPT, who then train others (i.e., Generation 2 providers). The present study will evaluate implementation and effectiveness outcomes of an EBPT for sleep and circadian dysfunction-the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C)-delivered to CMHC patients with serious mental illness by Generation 2 providers (i.e., trained and supervised within CMHCs via TTT). Specifically, we will investigate whether adapting TranS-C to fit CMHC contexts improves Generation 2 (a) patient outcomes and (b) providers' perceptions of fit.

methodsTTT will be implemented in nine CMHCs in California, USA (N = 60 providers; N = 130 patients) via facilitation. CMHCs are cluster-randomized by county to Adapted TranS-C or Standard TranS-C. Within each CMHC, patients are randomized to immediate TranS-C or usual care followed by delayed treatment with TranS-C (UC-DT). Aim 1 will assess the effectiveness of TranS-C (combined Adapted and Standard), compared to UC-DT, on improvements in sleep and circadian problems, functional impairment, and psychiatric symptoms for Generation 2 patients. Aim 2 will evaluate whether Adapted TranS-C is superior to Standard TranS-C with respect to Generation 2 providers' perceptions of fit. Aim 3 will evaluate whether Generation 2 providers' perceived fit mediates the relation between TranS-C treatment condition and patient outcomes. Exploratory analyses will (1) evaluate whether the effectiveness of TranS-C for patient outcomes is moderated by generation, (2) compare Adapted and Standard TranS-C on patient perceptions of credibility/improvement and PhenX Toolkit outcomes (e.g., substance use, suicidality), and (3) evaluate other possible moderators. DISCUSSION: This trial has potential to (a) inform the process of embedding local trainers and supervisors to expand delivery of a promising transdiagnostic treatment for sleep and circadian dysfunction, (b) add to the growing body of TTT literature by evaluating TTT outcomes with a novel treatment and population, and (c) advance our understanding of providers' perceptions of EBPT "fit" across TTT generations.

trial registrationClinicalTrials.gov identifier NCT05805657 . Registered on April 10, 2023.

Indexed as

Mental DisordersMental HealthCommunity Mental Health CentersHumansRandomized Controlled Trials as TopicSleepTreatment OutcomeAdaptationCircadianCommunity mental healthImplementationSerious mental illnessSleepSustainmentTrain-the-trainerTransdiagnostic

Identifiers

PMID37550730
PMCPMC10408147

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.