ArticleJournal of exposure science & environmental epidemiology2024
Ambient air pollution, genetic risk and telomere length in UK biobank.
Article in Journal of exposure science & environmental epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Modifying Role of Sustainable Diets on the Association Between Particulate Matter and Biological Aging: The Guangzhou Biobank Cohort Study.Aging cell · 2026Article
- Global, regional, and national burden of tracheal, bronchus, and lung cancer attributable to ambient particulate matter pollution among adults aged 70 and above in 1990-2021 and projected to 2044.Frontiers in public health · 2025Article
- Sarcopenia associated with increased risk of comorbidities among individuals with chronic kidney disease: insights from a prospective cohort.Frontiers in public health · 2025Article
- Monochrome Multiplex Quantitative PCR Telomere Length Measurement.Journal of visualized experiments : JoVE · 2024Article
- Risk relationship between leukocyte telomere length and constipation: a Mendelian randomization study.Frontiers in medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTelomere length (TL) is a biomarker of genomic aging. The evidence on the association between TL and air pollution was inconsistent. Besides, the modification effect of genetic susceptibility on the air pollution-TL association remains unknown.
objectiveWe aimed to evaluate the association of ambient air pollution with TL and further assess the modification effect of genetic susceptibility.
methods433,535 participants with complete data of TL and air pollutants in UK Biobank were included. Annual average exposure of NO
resultsCategorical exposure models and RCS models both indicated U-shaped (for NO IMPACT STATEMENT: Our study for the first time revealed a non-linear trend for the association between air pollution and telomere length. The genetic analyses suggested synergistic interactions between air pollution and genetic risk on the air pollution-TL association. These findings may shed new light on air pollution's health effects, offer suggestions for identifying at-risk individuals, and provide hints regarding further investigation into gene-environment interactions.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.