Evidence map›Paper›PMID 37550560›Full record

Trial reportAging clinical and experimental research2023

The role of qualification and quality management in the prescription of antipsychotics and potentially inappropriate medication (PIM) in nursing home residents in Germany: results of the HIOPP-3-iTBX study.

Regina Stolz, Olaf Krause, Ulrike Junius-Walker, Petra Thürmann, Angela Fuchs, Stefan Wilm, Anja Wollny, Franziska Rebentisch, Birgitt Wiese, Stefanie Joos and 1 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Aging clinical and experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Interventions for preventing falls in older people in care facilities.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Regina StolzInstitute for General Practice and Interprofessional Care, Medical Faculty, University Tübingen, Osianderstr. 5, 72076, Tübingen, Germany. regina.stolz@med.uni-tuebingen.de.ORCID http://orcid.org/0000-0003-1127-3090
Olaf KrauseInstitute for General Practice and Palliative Care, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Ulrike Junius-WalkerInstitute for General Practice and Palliative Care, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Petra ThürmannChair of Clinical Pharmacology, Faculty of Health, University Witten/Herdecke, Helios University Hospital Wuppertal University Witten/Herdecke, Heusnerstr. 40, 42283, Wuppertal, Germany.
Angela FuchsInstitute of General Practice, Medical Faculty, Centre for Health and Society, Heinrich-Heine University Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany.
Stefan WilmInstitute of General Practice, Medical Faculty, Centre for Health and Society, Heinrich-Heine University Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany.
Anja WollnyInstitute of General Practice, University Medical Center Rostock, Doberaner Strasse 142, P.O. Box 108880, 18057, Rostock, Germany.
Franziska RebentischInstitute of General Practice, University Medical Center Rostock, Doberaner Strasse 142, P.O. Box 108880, 18057, Rostock, Germany.
Birgitt WieseInstitute for General Practice and Palliative Care, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Stefanie JoosInstitute for General Practice and Interprofessional Care, Medical Faculty, University Tübingen, Osianderstr. 5, 72076, Tübingen, Germany.
Hannah HaumannInstitute for General Practice and Interprofessional Care, Medical Faculty, University Tübingen, Osianderstr. 5, 72076, Tübingen, Germany.
Medizinische Hochschule Hannover · DEHeinrich Heine University Düsseldorf · DEUniversity of Rostock · DEHelios Universitätsklinikum Wuppertal · DEUniversity of Tübingen · DE

Funding

Gemeinsame Bundesausschuss 01VSF16017
6 · The paper itself

Abstract

backgroundNursing home residents (NHR) show high rates of polypharmacy. The HIOPP-3-iTBX study is the first cRCT on medication optimization in nursing homes (NH) in Germany. The intervention did not result in a reduction of PIM and/or antipsychotics. This analysis looks at structure quality in the HIOPP-3-iTBX study participants.

aimsEvaluation of structure quality as part of a cluster-randomized controlled intervention study.

methodsStructure quality in multiprofessional teams from n = 44 NH (n = 44 NH directors, n = 91 family doctors (FD), and n = 52 pharmacies with n = 62 pharmacists) was assessed using self-designed questionnaires at baseline. Main aspects of the questionnaires related to the qualification of participants, quality management, the medication process and size of the facilities. All completed questionnaires were included. number of PIM/antipsychotics was drawn from the baseline medication analysis in 692 NHR. Data were analyzed by descriptive statistics and mixed model logistic regression.

resultsThe presence of a nurse with one of the additional qualifications pain nurse or Zertifiziertes Curriculum (Zercur) Geriatrie in the participating NH was associated with a lower risk for the prescription of PIM/antipsychotics. No association between any characteristic in the other participants at baseline was observed. CONCLUSIONS AND DISCUSSION: The results support the known role of nursing qualification in the quality and safety of care. Further studies need to look more closely at how use is made of the additional qualifications within the multiprofessional teams. Perspectively, the results can contribute to the development of quality standards in NH in Germany.

Indexed as

Antipsychotic AgentsPotentially Inappropriate Medication ListGermanyHumansInappropriate PrescribingNursing HomesPolypharmacyPrescriptionsAntipsychotic AgentsAntipsychoticsInterprofessional careMedication safetyNursing homePotentially inappropriate medicationQuality management

Identifiers

PMID37550560
PMCPMC10520111
OpenAlexW4385618366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.