ReviewNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2024
Digital and precision clinical trials: innovations for testing mental health medications, devices, and psychosocial treatments.
Review in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Digital sleep phenotype and wrist actigraphy in individuals at clinical high risk for psychosis and people with schizophrenia spectrum disorders: a systematic review and meta-analysis.BMJ mental health · 2025Pooled it
- High-Frequency, At-Home Monitoring of Drug Safety and Tolerability in Clinical Trials: Results From Studies of Fluvoxamine for COVID-19 Treatment.Clinical and translational science · 2025Trial
- Beyond RCTs-Better Research Designs and Methods for Psychosocial Efficacy Studies in Mental Health.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2026Review
- Digital Psychiatry with Virtual Reality and Augmented Reality: Recent Advances and Limitations.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026Review
- Generative AI for mental health: promise, risk and the path forward.BMJ digital health & AI · 2026Article
- Visualization of Experience Sampling Method Data in Mental Health: Qualitative Study of the Physicians' Perspective in Germany.Journal of medical Internet research · 2025Article
- An assessment of the informativeness of clinical trials in digital mental health.Npj mental health research · 2025Article
- Advancing Precision Oncology: Overcoming Treatment Resistance for Personalized Cancer Care.Current molecular medicine · 2025Article
- Estimating survival in data-driven phenotypes of mental health symptoms and peripheral biomarkers: A prospective study.Brain, behavior, & immunity - health · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
Abstract
Mental health treatment advances - including neuropsychiatric medications and devices, psychotherapies, and cognitive treatments - lag behind other fields of clinical medicine such as cardiovascular care. One reason for this gap is the traditional techniques used in mental health clinical trials, which slow the pace of progress, produce inequities in care, and undermine precision medicine goals. Newer techniques and methodologies, which we term digital and precision trials, offer solutions. These techniques consist of (1) decentralized (i.e., fully-remote) trials which improve the speed and quality of clinical trials and increase equity of access to research, (2) precision measurement which improves success rate and is essential for precision medicine, and (3) digital interventions, which offer increased reach of, and equity of access to, evidence-based treatments. These techniques and their rationales are described in detail, along with challenges and solutions for their utilization. We conclude with a vignette of a depression clinical trial using these techniques.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.