Evidence map›Paper›PMID 37550075›Full record

ArticleBMJ sexual & reproductive health2024

Red blood cell capacity of modern menstrual products: considerations for assessing heavy menstrual bleeding.

Emma DeLoughery, Alyssa C Colwill, Alison Edelman, Bethany Samuelson Bannow

Open access · bronzeAbstract read
In one paragraph

Article in BMJ sexual & reproductive health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
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  7. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Review
  8. Article
  9. Diagnosis and management of iron deficiency in females.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Review
  10. Article
  11. Article
  12. Quantifying menorrhagia and overview of nonsurgical management of heavy menstrual bleeding.Hematology. American Society of Hematology. Education Program · 2024
    Review
  13. Review
  14. Article
  15. Article
  16. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Emma DeLougheryDepartment of Medicine, Oregon Health & Science University, Portland, Oregon, USA.
Alyssa C ColwillDepartment of Obstetrics & Gynecology, Oregon Health & Science University, Portland, Oregon, USA.
Alison EdelmanDepartment of Obstetrics & Gynecology, Oregon Health & Science University, Portland, Oregon, USA.
Bethany Samuelson BannowDepartment of Medicine, Oregon Health & Science University, Portland, Oregon, USA samuelsb@ohsu.edu.ORCID http://orcid.org/0000-0002-9981-8990
Oregon Health & Science University · US

Funding

Scholars in Women's Health Research Across the LifespanK12HD043488 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI MYATT, LESLIE · 2002 to 2023
$10.4M
Oregon BIRCWH: Scholars in Women's Health Research Across the LifespanK12AR084221 · NIAMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI LESLIE MYATT · 2023 to 2026
$2.2M
NIAMS NIH HHS K12 AR084221NICHD NIH HHS K12 HD043488
6 · The paper itself

Abstract

backgroundHeavy menstrual bleeding affects up to one third of menstruating individuals and has a negative impact on quality of life. The diagnosis of heavy menstrual bleeding is based primarily on history taking, which is highly dependent on traditional disposable menstrual products such as pads and tampons. Only tampons undergo industry-regulated testing for absorption capacity. As use of alternative menstrual products is increasing, there is a need to understand how the capacity of these products compare to that of standard products.

methodsA variety of commercially available menstrual products (tampons, pads, menstrual cups and discs, and period underwear) were tested in the laboratory to determine their maximal capacity to absorb or fill using expired human packed red blood cells. The volume of blood necessary for saturation or filling of the product was recorded.

resultsOf the 21 individual menstrual hygiene products tested, a menstrual disc (Ziggy, Jiangsu, China) held the most blood of any product (80 mL). The perineal ice-activated cold pack and period underwear held the least (<3 mL each). Of the product categories tested, on average, menstrual discs had the greatest capacity (61 mL) and period underwear held the least (2 mL). Tampons, pads (heavy/ultra), and menstrual cups held similar amounts of blood (approximately 20-50 mL).

conclusionThis study found considerable variability in red blood cell volume capacity of menstrual products. This emphasises the importance of asking individuals about the type of menstrual products they use and how they use them. Further understanding of capacity of newer menstrual products can help clinicians better quantify menstrual blood loss, identify individuals who may benefit from additional evaluation, and monitor treatment.

Indexed as

MenorrhagiaErythrocytesFemaleHumansHygieneMenstrual Hygiene ProductsMenstruationQuality of Lifereproductive health

Identifiers

PMID37550075
PMCPMC10847380
OpenAlexW4385623461

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.