ArticleProceedings of the National Academy of Sciences of the United States of America2023
Reconstructing household transmission dynamics to estimate the infectiousness of asymptomatic influenza virus infections.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Role-specific household contact patterns in urban and rural China: Implications for influenza household transmission.Infectious Disease Modelling · 2027Article
- Live Attenuated Influenza Vaccine (LAIV) for Children for the Prevention of Influenza Illness in Sweden: A Cost-Effectiveness Analysis.Infectious diseases and therapy · 2026Article
- Influenza mitigation recommendations, symptoms, and viral RNA shedding durations-2023-24 and 2024-25 seasons.American journal of epidemiology · 2026Article
- Asymptomatic and Mildly Symptomatic Influenza Virus Infections by Season: Case-Ascertained Household Transmission Studies, United States, 2017-2023.The Journal of infectious diseases · 2025Article
- Community burden of acute respiratory infections in Shanghai, a longitudinal cohort study in respiratory pathogens, China, 2024-2027.BMJ open · 2025Article
- Estimating the generation time for influenza transmission using household data in the United States.Epidemics · 2025Article
- Routine immunization againstThe Lancet regional health. Southeast Asia · 2024Article
- Estimating the generation time for influenza transmission using household data in the United States.medRxiv : the preprint server for health sciences · 2024Article
- Asymptomatic and mildly symptomatic influenza virus infections by season -- Case-ascertained household transmission studies, United States, 2017-2023.medRxiv : the preprint server for health sciences · 2024Article
- Evaluating equity-promoting interventions to prevent race-based inequities in influenza outcomes.medRxiv : the preprint server for health sciences · 2024Article
- The role of asymptomatic infections in influenza transmission: what do we really know.The Lancet. Infectious diseases · 2024Review
- High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4Frontiers in immunology · 2024Article
- Reconstructing household transmission dynamics to estimate the infectiousness of asymptomatic influenza virus infections.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There has long been controversy over the potential for asymptomatic cases of the influenza virus to have the capacity for onward transmission, but recognition of asymptomatic transmission of COVID-19 stimulates further research into this topic. Here, we develop a Bayesian methodology to analyze detailed data from a large cohort of 727 households and 2515 individuals in the 2009 pandemic influenza A(H1N1) outbreak in Hong Kong to characterize household transmission dynamics and to estimate the relative infectiousness of asymptomatic versus symptomatic influenza cases. The posterior probability that asymptomatic cases [36% of cases; 95% credible interval (CrI): 32%, 40%] are less infectious than symptomatic cases is 0.82, with estimated relative infectiousness 0.57 (95% CrI: 0.11, 1.54). More data are required to strengthen our understanding of the contribution of asymptomatic cases to the spread of influenza.
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