Evidence map›Paper›PMID 37549264›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Insight into the mechanism of H

Jun Weng, Xiaoming Zhou, Pattama Wiriyasermkul, Zhenning Ren, Kehan Chen, Eva Gil-Iturbe, Ming Zhou, Matthias Quick

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
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  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jun Weng *Department of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY 10032.
Xiaoming Zhou *Department of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY 10032.ORCID 0000-0001-8866-7245
Pattama Wiriyasermkul *Department of Psychiatry, Columbia University Irving Medical Center, New York, NY 10032.ORCID 0000-0001-7068-7969
Zhenning RenVerna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030.
Kehan ChenVerna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030.
Eva Gil-IturbeDepartment of Psychiatry, Columbia University Irving Medical Center, New York, NY 10032.ORCID 0000-0002-4046-5756
Ming ZhouDepartment of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY 10032.ORCID 0000-0001-7198-165X
Matthias QuickDepartment of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY 10032.ORCID 0000-0002-8620-827X
Columbia University Irving Medical Center · USBaylor College of Medicine · US

Funding

Structural mechanism of K channel modulation by cellular redox stateR01HL086392 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ZHOU, MING · 2006 to 2018
$3.9M
Structure and mechanism of mammalian stearoyl-CoA desaturasesR01DK122784 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI TSAI, AH-LIM, ZHOU, MING · 2019 to 2023
$3.2M
Molecular mechanism of nucleobase/vitamin C transportersR01GM119396 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI QUICK, MATTHIAS · 2016 to 2020
$1.9M
NHLBI NIH HHS R01 HL086392NIDDK NIH HHS R01 DK122784NIGMS NIH HHS R01 GM119396
6 · The paper itself

Abstract

Members of the nucleobase/ascorbic acid transporter (NAT) gene family are found in all kingdoms of life. In mammals, the concentrative uptake of ascorbic acid (vitamin C) by members of the NAT family is driven by the Na

Indexed as

Ascorbic AcidPurinesAnimalsBinding SitesBiological TransportMammalsMutationAscorbic AcidPurinesH+-coupled transportNAT gene familynucleobasesPurTCpX-ray crystallography

Identifiers

PMID37549264
PMCPMC10438392
OpenAlexW4385618221

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.