ArticlePLoS genetics2023
Nascent evolution of recombination rate differences as a consequence of chromosomal rearrangements.
Article in PLoS genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Kinetochore size correlates with chromosome size in Star of Bethlehem (Ornithogalum kochii Parl., Asparagaceae).Plant biology (Stuttgart, Germany) · 2026Article
- Beyond inversions and deletions: the evolutionary and functional insights from translocations, fissions, and fusions in animal genomes.Heredity · 2026Review
- Rapid genome modifications including chromosomal fusions and large-scale inversions are key features in Arctic codfish species.Genome biology · 2026Article
- Genetic legacy and recent cross of two ancient lineages underlie the rebound of the world's rarest primate.Science advances · 2026Article
- Evolution of Hybrid Inviability Associated With Chromosome Fusions.Molecular ecology · 2025Article
- Genomics of Neotropical biodiversity indicators: Two butterfly radiations with rampant chromosomal rearrangements and hybridization.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Genomic regions of current low hybridisation mark long-term barriers to gene flow in scarce swallowtail butterflies.PLoS genetics · 2025Article
- Centromere diversity and its evolutionary impacts on plant karyotypes and plant reproduction.The New phytologist · 2025Review
- Genomic Monitoring of a Reintroduced Butterfly Uncovers Contrasting Founder Lineage Survival.Evolutionary applications · 2025Article
- Incomplete recombination suppression fuels extensive haplotype diversity in a butterfly colour pattern supergene.PLoS biology · 2025Article
- Neo-Sex Chromosome Evolution in Treehoppers Despite Long-Term X Chromosome Conservation.Genome biology and evolution · 2024Article
- Do chromosome rearrangements fix by genetic drift or natural selection? Insights from Brenthis butterflies.Molecular ecology · 2024Article
- Annelid Comparative Genomics and the Evolution of Massive Lineage-Specific Genome Rearrangement in Bilaterians.Molecular biology and evolution · 2024Article
- Meiotic drive against chromosome fusions in butterfly hybrids.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2024Article
- GC Content Across Insect Genomes: Phylogenetic Patterns, Causes and Consequences.Journal of molecular evolution · 2024Article
- The fine-scale recombination rate variation and associations with genomic features in a butterfly.Genome research · 2023Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reshuffling of genetic variation occurs both by independent assortment of chromosomes and by homologous recombination. Such reshuffling can generate novel allele combinations and break linkage between advantageous and deleterious variants which increases both the potential and the efficacy of natural selection. Here we used high-density linkage maps to characterize global and regional recombination rate variation in two populations of the wood white butterfly (Leptidea sinapis) that differ considerably in their karyotype as a consequence of at least 27 chromosome fissions and fusions. The recombination data were compared to estimates of genetic diversity and measures of selection to assess the relationship between chromosomal rearrangements, crossing over, maintenance of genetic diversity and adaptation. Our data show that the recombination rate is influenced by both chromosome size and number, but that the difference in the number of crossovers between karyotypes is reduced as a consequence of a higher frequency of double crossovers in larger chromosomes. As expected from effects of selection on linked sites, we observed an overall positive association between recombination rate and genetic diversity in both populations. Our results also revealed a significant effect of chromosomal rearrangements on the rate of intergenic diversity change between populations, but limited effects on polymorphisms in coding sequence. We conclude that chromosomal rearrangements can have considerable effects on the recombination landscape and consequently influence both maintenance of genetic diversity and efficiency of selection in natural populations.
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