Evidence map›Paper›PMID 37548874›Full record

ArticleVeterinary research communications2024

Seroprevalence of anti-SARS-CoV-2 antibodies in household domestic ferrets (Mustela putorius furo) in Spain, 2019-2023.

Jacobo Giner, María Eugenia Lebrero, Michele Trotta, Pablo Rueda, Laura Vilalta, Maite Verde, Ramón Hurtado-Guerrero, Julián Pardo, Delia Lacasta, Llipsy Santiago and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Veterinary research communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Jacobo GinerClinical Immunology Laboratory, Veterinary Faculty, University of Zaragoza, 50013, Zaragoza, Spain.
María Eugenia LebreroDepartment of Animal Pathology, Veterinary Faculty, University of Zaragoza, Zaragoza, Spain.
Michele TrottaClinical Immunology Laboratory, Veterinary Faculty, University of Zaragoza, 50013, Zaragoza, Spain.
Pablo RuedaClinical Immunology Laboratory, Veterinary Faculty, University of Zaragoza, 50013, Zaragoza, Spain.
Laura VilaltaHospital Veterinari Canis, Girona, Spain.
Maite VerdeClinical Immunology Laboratory, Veterinary Faculty, University of Zaragoza, 50013, Zaragoza, Spain.
Ramón Hurtado-GuerreroInstitute for Biocomputation and Physics of Complex Systems (BIFI), University of Zaragoza, Edificio I+D, Campus Rio Ebro, Zaragoza, Spain.
Julián PardoAragon Health Research Institute (IIS Aragón), Zaragoza, Spain.
Delia LacastaDepartment of Animal Pathology, Veterinary Faculty, University of Zaragoza, Zaragoza, Spain.
Llipsy SantiagoAragon Health Research Institute (IIS Aragón), Zaragoza, Spain.
Maykel AriasAragon Health Research Institute (IIS Aragón), Zaragoza, Spain.
Natacha Peña-FresnedaAragon Health Research Institute (IIS Aragón), Zaragoza, Spain.
Andrés MontesinosDepartment of Animal Medicine and Surgery, Veterinary Faculty, Univerisdad Complutense Madrid, Madrid, Spain.
María D PérezInstituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), Zaragoza, Spain.
Antonio FernándezClinical Immunology Laboratory, Veterinary Faculty, University of Zaragoza, 50013, Zaragoza, Spain.
Sergio Villanueva-SazClinical Immunology Laboratory, Veterinary Faculty, University of Zaragoza, 50013, Zaragoza, Spain. svs@unizar.es.
Universidad de Zaragoza · ESInstituto de Salud Carlos III · ESCentro de Investigación y Tecnología Agroalimentaria de Aragón · ESClínica Girona · ESInstituto de Investigación Sanitaria Aragón · ESUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 is the causal agent of Coronavirus Disease 2019 (COVID-19) in humans that emerged in late 2019. This virus is able to infect humans and different animal species. Among pets, cats and ferrets are more susceptible to be infected by the SARS-CoV-2. Epidemiological studies are an important tool to provide information under natural conditions of exposure to SARS-CoV-2 virus. In comparison to cats, limited epidemiological studies have been performed in domestic ferrets (Mustela putorius furo) reporting the presence of antibodies in this species. This study analysed the presence of anti-SARS-CoV-2 antibodies in 432 cliend-owned ferrets from different geographical areas of Spain during the different waves of COVID-19 outbreaks from December 2019 to May 2023 (42 months). For this purpose, anti-SARS-CoV-2 antibodies were detected by an enzyme-linked immunosorbent method (ELISA) using the receptor binding domain (RBD) of Spike antigen and confirmed by serum virus neutralization assay. Eighteen of the 432 ferrets included were seroreactive by the in-house ELISA (4.17%, 95% Confidence Interval (CI): 2.65-6.49). In this sense, the wave of COVID-19 with the higher number of seropositive ferrets occurred during the seventh wave when the different Omicron subvariants were the dominant virus variants. Our results suggest that the risk of SARS-CoV-2 transmission in domestic ferrets in natural conditions is low. Further research is need to evaluate the potential risk of transmission of SARS-CoV-2 from human to pets.

Indexed as

COVID-19FerretsAnimalsAntibodies, ViralHumansSARS-CoV-2Seroepidemiologic StudiesSpainAntibodies, ViralELISAFerretSARS-CoV-2SerologySpainVNT

Identifiers

PMID37548874
PMCPMC10811151
OpenAlexW4385620564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.