Evidence map›Paper›PMID 37548873›Full record

ArticleBiomechanics and modeling in mechanobiology2024

Association between jejunal remodeling in fasting rats and hypersensitivity of intestinal afferent nerves to mechanical stimulation.

Lingxia Bao, Jingbo Zhao, Hans Gregersen

Abstract read
PubMed Publisher
In one paragraph

Article in Biomechanics and modeling in mechanobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Lingxia BaoChongqing University of Posts and Telecommunications, Chongqing, 400065, China.
Jingbo ZhaoGIOME and the Key Laboratory for Biorheological Science and Technology of Ministry of Education, College of Bioengineering at Chongqing University, Chongqing, 400044, China. jingbozhao@hotmail.com.
Hans GregersenGIOME and the Key Laboratory for Biorheological Science and Technology of Ministry of Education, College of Bioengineering at Chongqing University, Chongqing, 400044, China.
California Medical Innovations Institute · USChongqing University · CNMinistry of Education · TH

Funding

Chongqing Municipal Bureau of Science and Technology Foundation sl202100000303Chongqing University of Posts and Telecommunications Foundation A2022020Grant from Chongqing Science and Technology Commission cstc2013kjrcljrccj10003
6 · The paper itself

Abstract

Remodeling of Intestinal properties and hypersensitivity of intestinal afferents to mechanical stimulation were previously demonstrated in a fasting rat model. Other studies investigated the association between mechanical and histological remodeling during fasting. This study aimed to further explore the relationship between the jejunal remodeling and intestinal afferent hypersensitivity by combining afferent nerve recordings with histological and mechanical data. Eight male Sprague Dawley rats had no access to food for 7 days (Fasting group). Seven male rats served as controls (Control group). Jejunal segments were studied in vitro in an organ bath for analysis of afferent signaling and for analysis of mechanical and histomorphological parameters. Correlation analyses were done to analyze association between nerve activity (spike rate increase ratio, SRIR) at distension levels of 20, 40 and 80 cmH

Indexed as

IntestinesJejunumAnimalsBiomechanical PhenomenaFastingMaleRatsRats, Sprague-DawleyFastingHistomorphological remodelingHypersensitivityIntestinal afferentMechanical stress and strain

Identifiers

PMID37548873
OpenAlexW4385620400

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.