Evidence map›Paper›PMID 37548705›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

Necrotizing external otitis: diagnostic clues in the emergency department.

Miguel Vaca, María M Medina, Adela I Cordero, Rubén Polo, Cecilia Pérez, Sandra Domínguez, Gonzalo de Los Santos

Abstract readCase Reports
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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. [Expert consensus on diagnosis and treatment of external auditory canal cholesteatoma(2026)].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Miguel VacaDepartment of Otolaryngology, Hospital Universitario Ramón Y Cajal, Ctra. Colmenar Km 9.100, 28034, Madrid, Spain. miguel.vaca.gonzalez@gmail.com.ORCID http://orcid.org/0000-0001-9808-1846
María M MedinaDepartment of Otolaryngology, Hospital Universitario Ramón Y Cajal, Ctra. Colmenar Km 9.100, 28034, Madrid, Spain.
Adela I CorderoDepartment of Otolaryngology, Hospital Universitario Ramón Y Cajal, Ctra. Colmenar Km 9.100, 28034, Madrid, Spain.
Rubén PoloDepartment of Otolaryngology, Hospital Universitario Ramón Y Cajal, Ctra. Colmenar Km 9.100, 28034, Madrid, Spain.
Cecilia PérezDepartment of Otolaryngology, Hospital Universitario Ramón Y Cajal, Ctra. Colmenar Km 9.100, 28034, Madrid, Spain.
Sandra DomínguezDepartment of Otolaryngology, Hospital Universitario Ramón Y Cajal, Ctra. Colmenar Km 9.100, 28034, Madrid, Spain.
Gonzalo de Los SantosDepartment of Otolaryngology, Hospital Universitario Ramón Y Cajal, Ctra. Colmenar Km 9.100, 28034, Madrid, Spain.
Hospital Universitario Ramón y Cajal · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe assessment of necrotizing external otitis requires a high index of suspicion by the attending physician. The purpose of the study is to determine the accuracy of parameters available at the Emergency Department for the diagnosis of this pathology.

methodsRetrospective diagnostic accuracy study. Patients consulting at the Emergency Department for longstanding ear swelling, severe otalgia, and failure to respond to topical treatment were included. Otoscopy, physical examination, CT appearance, and analytical results were tested for the diagnosis of necrotizing external otitis, using nuclear imaging as gold standard. Sensitivity, specificity, likelihood ratios and ROC curves were calculated.

results24 patients were included; 13 cases were necrotizing external otitis, and 11 cases were other external ear pathologies. Erythrocyte sedimentation rate and C-reactive protein levels were significantly associated with necrotizing external otitis (AUC 0.92 p < 0.001, and 0.8 p < 0.001). Positive likelihood ratios were 10.15 for values of erythrocyte sedimentation rate over 26 mm/h, and 8.25 for C-reactive protein levels over 10 mg/L. Negative likelihood ratios were 0.08 and 0.28, respectively. These results were significant. The rest of clinical and radiological parameters were less accurate.

conclusionsErythrocyte sedimentation rate and C-reactive protein are useful parameters in the evaluation of a case of longstanding otitis with clinical suspicion of necrotizing external otitis. If any of them is elevated, the probability of suffering this condition is significantly increased. If they are within normal ranges, an alternative diagnosis should be sought.

Indexed as

Otitis ExternaC-Reactive ProteinEar, ExternalEmergency Service, HospitalHumansRetrospective StudiesC-Reactive ProteinExternal otitisMalignant external otitisNecrotizing external otitisSkull base osteomyelitis

Identifiers

PMID37548705
OpenAlexW4385620874

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.