Evidence map›Paper›PMID 37548032›Full record

ArticleJournal of geriatric psychiatry and neurology2024

Atypical Neuropsychiatric Presentation of FTD-ALS Caused by a Pathogenic Repeat Expansion in

Marissa A LeBlanc, Amy Gough, Andrea L Rideout, Sarah Dyack, Kathleen Singh, Meagan MacNeil

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of geriatric psychiatry and neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Marissa A LeBlancDepartment of Psychiatry, Dalhousie University, Halifax, NS, Canada.ORCID 0009-0002-6410-9577
Amy GoughDepartment of Psychiatry, Dalhousie University, Halifax, NS, Canada.
Andrea L RideoutIWK Maritime Medical Genetics, Halifax, NS, Canada.
Sarah DyackNova Scotia Health, Halifax, NS, Canada.
Kathleen SinghDepartment of Psychiatry, Dalhousie University, Halifax, NS, Canada.
Meagan MacNeilDepartment of Psychiatry, Dalhousie University, Halifax, NS, Canada.
Dalhousie University · CAIzaak Walton Killam Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The case report describes the presentation of a 42-year-old male ultimately diagnosed with FTD-ALS caused by a genetic mutation, who initially presented with atypical psychiatric symptoms. Given that the initial clinical manifestations of FTD-ALS can be quite variable, the diagnosis is often challenging; the case report aims to highlight several key considerations in the diagnostic assessment, including genetic testing in order to guide clinicians in more timely diagnosis and ultimately improve patient care.

Indexed as

Amyotrophic Lateral SclerosisFrontotemporal DementiaAdultC9orf72 ProteinDNA Repeat ExpansionHumansMaleMutationC9orf72 ProteinC9orf72 protein, humanc9orf72frontotemporal dementiapsychosis

Identifiers

PMID37548032
PMCPMC10802081
OpenAlexW4385620958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.