Evidence map›Paper›PMID 37547880›Full record

ArticleCrystal growth & design2023

Design and Validation of a Droplet-based Microfluidic System To Study Non-Photochemical Laser-Induced Nucleation of Potassium Chloride Solutions.

Vikram Korede, Frederico Marques Penha, Vincent de Munck, Lotte Stam, Thomas Dubbelman, Nagaraj Nagalingam, Maheswari Gutta, PingPing Cui, Daniel Irimia, Antoine E D M van der Heijden and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Crystal growth & design, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Vikram KoredeProcess and Energy Department, Delft University of Technology, Leeghwaterstraat 39, 2628 CB Delft, The Netherlands.ORCID https://orcid.org/0000-0002-6276-3789
Frederico Marques PenhaDepartment of Chemical Engineering, KTH Royal Institute of Technology, Teknikringen 42, 114-28 Stockholm, Sweden.ORCID https://orcid.org/0000-0001-7614-8448
Vincent de MunckProcess and Energy Department, Delft University of Technology, Leeghwaterstraat 39, 2628 CB Delft, The Netherlands.
Lotte StamProcess and Energy Department, Delft University of Technology, Leeghwaterstraat 39, 2628 CB Delft, The Netherlands.
Thomas DubbelmanProcess and Energy Department, Delft University of Technology, Leeghwaterstraat 39, 2628 CB Delft, The Netherlands.
Nagaraj NagalingamProcess and Energy Department, Delft University of Technology, Leeghwaterstraat 39, 2628 CB Delft, The Netherlands.ORCID https://orcid.org/0000-0003-4497-3691
Maheswari GuttaProcess and Energy Department, Delft University of Technology, Leeghwaterstraat 39, 2628 CB Delft, The Netherlands.ORCID https://orcid.org/0000-0002-5697-3296
PingPing CuiSchool of Chemical Engineering and Technology, State Key Laboratory of Chemical Engineering, Tianjin University, 300072 Tianjin, People's Republic of China.
Daniel IrimiaProcess and Energy Department, Delft University of Technology, Leeghwaterstraat 39, 2628 CB Delft, The Netherlands.ORCID https://orcid.org/0000-0001-6131-6912
Antoine E D M van der HeijdenProcess and Energy Department, Delft University of Technology, Leeghwaterstraat 39, 2628 CB Delft, The Netherlands.
Herman J M KramerProcess and Energy Department, Delft University of Technology, Leeghwaterstraat 39, 2628 CB Delft, The Netherlands.ORCID https://orcid.org/0000-0003-3580-8432
Hüseyin Burak EralProcess and Energy Department, Delft University of Technology, Leeghwaterstraat 39, 2628 CB Delft, The Netherlands.ORCID https://orcid.org/0000-0003-3193-452X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-photochemical laser-induced nucleation (NPLIN) has emerged as a promising primary nucleation control technique offering spatiotemporal control over crystallization with potential for polymorph control. So far, NPLIN was mostly investigated in milliliter vials, through laborious manual counting of the crystallized vials by visual inspection. Microfluidics represents an alternative to acquiring automated and statistically reliable data. Thus we designed a droplet-based microfluidic platform capable of identifying the droplets with crystals emerging upon Nd:YAG laser irradiation using the deep learning method. In our experiments, we used supersaturated solutions of KCl in water, and the effect of laser intensity, wavelength (1064, 532, and 355 nm), solution supersaturation (

Identifiers

PMID37547880
PMCPMC10401630

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.