Evidence map›Paper›PMID 37547763›Full record

ReviewOncology research2023

Circulating tumor cells and circulating tumor DNA in breast cancer diagnosis and monitoring.

Effat Alemzadeh, Leila Allahqoli, Hamideh Dehghan, Afrooz Mazidimoradi, Alireza Ghasempour, Hamid Salehiniya

Abstract readReview
In one paragraph

Review in Oncology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Oncolytic viruses: advanced strategies in cancer therapy.Signal transduction and targeted therapy · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Effat AlemzadehInfectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, 9717853577, Iran.
Leila AllahqoliMidwifery Department, Ministry of Health and Medical Education, Tehran, 9413933336, Iran.
Hamideh DehghanStudent Research Committee, Birjand University of Medical Sciences, Birjand, 9717853577, Iran.
Afrooz MazidimoradiDepartment of Health Assistant, Shiraz University of Medical Sciences, Shiraz, 7134814336, Iran.
Alireza GhasempourStudent Research Committee, Birjand University of Medical Sciences, Birjand, 9717853577, Iran.
Hamid SalehiniyaSocial Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, 32048321, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liquid biopsy, including both circulating tumor cells and circulating tumor DNA, is becoming more popular as a diagnostic tool in the clinical management of breast cancer. Elevated concentrations of these biomarkers during cancer treatment may be used as markers for cancer progression as well as to understand the mechanisms underlying metastasis and treatment resistance. Thus, these circulating markers serve as tools for cancer assessing and monitoring through a simple, non-invasive blood draw. However, despite several study results currently noting a potential clinical impact of ctDNA mutation tracking, the method is not used clinically in cancer diagnosis among patients and more studies are required to confirm it. This review focuses on understanding circulating tumor biomarkers, especially in breast cancer.

Indexed as

Breast NeoplasmsCirculating Tumor DNANeoplastic Cells, CirculatingBiomarkers, TumorFemaleHumansLiquid BiopsyMutationBiomarkers, TumorCirculating Tumor DNABreast cancerCirculating tumor cellsCirculating tumor DNALiquid biopsy

Identifiers

PMID37547763
PMCPMC10398400

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.