Evidence map›Paper›PMID 37547751›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2023

European Society for Organ Transplantation (ESOT) Consensus Statement on the Role of Pancreas Machine Perfusion to Increase the Donor Pool for Beta Cell Replacement Therapy.

Joana Ferrer-Fàbrega, Benoît Mesnard, Franka Messner, Jason B Doppenberg, Cinthia Drachenberg, Marten A Engelse, Paul R V Johnson, Henri G D Leuvenink, Gabriel C Oniscu, Vassilios Papalois and 11 more

Abstract readConsensus Statement
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Editorial: Current developments in artificial organs and engineeredTransplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  5. Improved Rat Heart Preservation Using High-Pressure Gaseous Perfusion with Oxygen-Xenon Mixture.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. 2024: A Year in Review.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Joana Ferrer-FàbregaHepatobiliopancreatic Surgery and Liver and Pancreatic Transplantation Unit, Department of Surgery, Institute Clínic of Digestive and Metabolic Diseases (ICMDiM), Hospital Clínic, University of Barcelona, Barcelona, Spain.
Benoît MesnardDepartment of Urology and Transplantation Surgery, Nantes University Hospital, Nantes, France.
Franka MessnerDepartment of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Jason B DoppenbergTransplantation Center, Leiden University Medical Center, Leiden, Netherlands.
Cinthia DrachenbergDepartment of Pathology, University of Maryland School of Medicine, Baltimore, MD, United States.
Marten A EngelseTransplantation Center, Leiden University Medical Center, Leiden, Netherlands.
Paul R V JohnsonResearch Group for Islet Transplantation, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.
Henri G D LeuveninkDepartment of Surgery, University Medical Center Groningen, Groningen, Netherlands.
Gabriel C OniscuTransplant Division, Department of Clinical Science, Intervention and Technology - CLINTEC, Karolinska Institutet, Stockholm, Sweden.
Vassilios PapaloisImperial College Renal and Transplant Centre, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
Rutger J PloegOxford Transplant Centre, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.
Trevor W ReichmanAjmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto, ON, Canada.
William E ScottTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Fabio VistoliDivision of General Surgery and Transplantation, University of Pisa, Pisa, Italy.
Thierry BerneyDivision of Transplantation, Department of Surgery, University of Geneva Hospitals, Geneva, Switzerland.
Daniel Jacobs-Tulleneers-ThevissenDiabetes Research Center, Vrije Universiteit Brussel, Brussels, Belgium.
Nicos KessarisDepartment of Nephrology and Transplantation, Guy's Hospital, London, United Kingdom.
Annemarie WeissenbacherDepartment of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Ann Etohan OgbemudiaOxford Transplant Centre, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.
Steve WhiteDepartment of HPB and Transplant Surgery, NIHR BTRU in Organ Donation and Transplantation, The Freeman Hospital, The University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom.
Julien BranchereauDepartment of Urology and Transplantation Surgery, Nantes University Hospital, Nantes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The advent of Machine Perfusion (MP) as a superior form of preservation and assessment for cold storage of both high-risk kidney's and the liver presents opportunities in the field of beta-cell replacement. It is yet unknown whether such techniques, when applied to the pancreas, can increase the pool of suitable donor organs as well as ameliorating the effects of ischemia incurred during the retrieval process. Recent experimental models of pancreatic MP appear promising. Applications of MP to the pancreas, needs refinement regarding perfusion protocols and organ viability assessment criteria. To address the "Role of pancreas machine perfusion to increase the donor pool for beta cell replacement," the European Society for Organ Transplantation (ESOT) assembled a dedicated working group comprising of experts to review literature pertaining to the role of MP as a method of improving donor pancreas quality as well as quantity available for transplant, and to develop guidelines founded on evidence-based reviews in experimental and clinical settings. These were subsequently refined during the Consensus Conference when this took place in Prague.

Indexed as

Organ PreservationOrgan TransplantationHumansPancreasPerfusionTissue Donorsischemia-reperfusion injuryislet transplantationmachine perfusionpersufflationwhole pancreas transplantation

Identifiers

PMID37547751
PMCPMC10402633

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.