Evidence map›Paper›PMID 37547536›Full record

ArticleKidney international reports2023

Common Risk Variants in

Mallory L Downie, Sanjana Gupta, Catalin Voinescu, Adam P Levine, Omid Sadeghi-Alavijeh, Stephanie Dufek-Kamperis, Jingjing Cao, Martin Christian, Jameela A Kari, Shenal Thalgahagoda and 8 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Novel immune-related susceptibility loci associated with pediatric steroid-sensitive nephrotic syndrome identified by a transethnic genome-wide association study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Article
  3. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 6 countries.

Mallory L DownieDepartment of Renal Medicine, University College London, London, UK.
Sanjana GuptaDepartment of Renal Medicine, University College London, London, UK.
Catalin VoinescuDepartment of Renal Medicine, University College London, London, UK.
Adam P LevineDepartment of Pathology, University College London, London, UK.
Omid Sadeghi-AlavijehDepartment of Renal Medicine, University College London, London, UK.
Stephanie Dufek-KamperisDepartment of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark.
Jingjing CaoDivision of Nephrology, Department of Pediatrics, The Hospital for Sick Children, Toronto, Canada.
Martin ChristianNottingham Children's Hospital, Nottingham, UK.
Jameela A KariPediatric Nephrology Centre of Excellence, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Shenal ThalgahagodaDepartment of Pediatrics, University of Peradeniya, Peradeniya, Sri Lanka.
Randula RanawakaDepartment of Pediatrics, University of Peradeniya, Peradeniya, Sri Lanka.
Asiri AbeyagunawardenaDepartment of Pediatrics, University of Peradeniya, Peradeniya, Sri Lanka.
Rasheed GbadegesinDepartment of Pediatrics, Duke University School of Medicine, Durham, North Carolina, USA.
Rulan ParekhDivision of Nephrology, Department of Pediatrics, The Hospital for Sick Children, Toronto, Canada.
Robert KletaDepartment of Renal Medicine, University College London, London, UK.
Detlef BockenhauerDepartment of Renal Medicine, University College London, London, UK.
Horia C StanescuDepartment of Renal Medicine, University College London, London, UK.
Daniel P GaleDepartment of Renal Medicine, University College London, London, UK.
University College London · GBUniversity of Peradeniya · LKHospital for Sick Children · CAAarhus University Hospital · DKDuke University · USGreat Ormond Street Hospital for Children NHS Foundation Trust · GBKing Abdulaziz University · SA

Funding

Medical Research Council MR/S021329/1
6 · The paper itself

Abstract

Introduction: Steroid-sensitive nephrotic syndrome (SSNS) is the most common form of kidney disease in children worldwide. Genome-wide association studies (GWAS) have demonstrated the association of SSNS with genetic variation at Methods: We conducted a GWAS in a cohort of Sri Lankan individuals comprising 420 pediatric patients with SSNS and 2339 genetic ancestry matched controls obtained from the UK Biobank. We then performed a transethnic meta-analysis with a previously reported European cohort of 422 pediatric patients and 5642 controls. Results: Our GWAS confirmed the previously reported association of SSNS with Conclusions: Common variation in

Indexed as

AHI1GWASHLApediatric nephrologySSNS

Identifiers

PMID37547536
PMCPMC10403666
OpenAlexW4378471960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.