Evidence map›Paper›PMID 37547356›Full record

ArticleHealth science reports2023

The association between HIV infection and precancerous cervical lesion. A systematic review and meta-analysis of case-control studies.

Habtamu Geremew, Hiwot Tesfa, Misganaw A Mengstie, Chalachew Gashu, Yoseph Kassa, Abraham Negash, Anteneh M Dessie, Demeke Geremew

Open access · goldAbstract read
In one paragraph

Article in Health science reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Habtamu GeremewCollege of Health Science Oda Bultum University Chiro Ethiopia.ORCID 0000-0002-9027-9847
Hiwot TesfaDepartment of Public Health, College of Medicine and Health Sciences Injibara University Injibara Ethiopia.
Misganaw A MengstieDepartment of Biochemistry, College of Medicine and Health Sciences Debre Tabor University Debre Tabor Ethiopia.ORCID 0000-0002-9711-8640
Chalachew GashuDepartment of Statistics, College of Natural and Computational Science Oda Bultum University Chiro Ethiopia.
Yoseph KassaDepartment of Statistics, College of Natural and Computational Science Oda Bultum University Chiro Ethiopia.
Abraham NegashSchool of Nursing and Midwifery, College of Health and Medical Sciences Haramaya University Harar Ethiopia.
Anteneh M DessieDepartment of Public Health, College of Health Sciences Debre Tabor University Debre Tabor Ethiopia.ORCID 0000-0002-5919-9670
Demeke GeremewDepartment of Medical Laboratory Science, Immunology and Molecular Biology Unit, College of Medicine and Health Sciences Bahir Dar University Bahir Dar Ethiopia.
Debre Tabor University · ETBahir Dar University · ETHaramaya University · ETJigjiga University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The effect of human immunodeficiency virus (HIV) on precancerous cervical lesion is not consistent across studies. Besides to the variability in the presence of a significant association between HIV and precancerous cervical lesion, the reported strengths are inconsistent among studies that report a significant association. Therefore, we sought to determine the impact of HIV on women's risk of precancerous cervical lesion by conducting a systematic review and meta-analysis of case-control studies in Ethiopia. Methods: Relevant articles were systematically searched on African Journals Online, Cochrane Library, Science Direct, Google Scholar, and PubMed from January 1, 2023, to February 20, 2023. After critical appraisal, pertinent data were extracted into an Excel spreadsheet and then exported to STATA 14 for further statistical analysis. The pooled effect size was estimated using the random-effect model. The Egger's regression test and Results: Ten case-control studies with a total of 3035 participants (992 cases and 2043 controls) were involved in this meta-analysis. According to our analysis, HIV-infected women were 2.86 times more likely to develop precancerous cervical lesion as compared with their counterparts (odds ratio: 2.86, 95% confidence interval: 1.79, 4.58). Conclusion: We found that HIV-infected women have a higher risk of precancerous cervical lesion. Thus, targeted screening programs should be considered to reduce the burden of cervical cancer among HIV-infected women in Ethiopia.

Indexed as

EthiopiaHIV infectionMeta‐analysisPrecancerous cervical lesion

Identifiers

PMID37547356
PMCPMC10397473
OpenAlexW4385551177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.