Evidence map›Paper›PMID 37547256›Full record

ArticleFrontiers in cardiovascular medicine2023

Asymptomatic people with well-controlled HIV do not have abnormal left ventricular global longitudinal strain.

Jennifer F Hoy, Sue J Lee, Janine M Trevillyan, Elizabeth M Dewar, Janine Roney, Anthony Dart, Yan Yang

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jennifer F HoyDepartment of Infectious Diseases, Alfred Health and Monash University, Melbourne, VIC, Australia.
Sue J LeeDepartment of Infectious Diseases, Alfred Health and Monash University, Melbourne, VIC, Australia.
Janine M TrevillyanDepartment of Infectious Diseases, Alfred Health and Monash University, Melbourne, VIC, Australia.
Elizabeth M DewarDepartment of Cardiology, Alfred Health, Melbourne, VIC, Australia.
Janine RoneyDepartment of Infectious Diseases, Alfred Health and Monash University, Melbourne, VIC, Australia.
Anthony DartDepartment of Cardiology, Alfred Health, Melbourne, VIC, Australia.
Yan YangDepartment of Cardiology, Alfred Health, Melbourne, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Previous studies have reported impairment in systolic and diastolic function in people with HIV (PWHIV). Our aim was to determine if echocardiographically measured left ventricular (LV) global longitudinal strain (GLS) is abnormal in asymptomatic PWHIV. Methods: A cross-sectional study of PWHIV ( Results: All PWHIV were receiving antiretroviral therapy (ART) for a median of 12 years (IQR: 6.9, 22.4), the majority with good virological control (87% suppressed) and without immunological compromise (median CD4 598 cells/µl, IQR: 388, 841). Compared with controls of similar age and gender, there was no difference in GLS [mean GLS -20.3% (SD 2.5%) vs. -21.0% (SD 2.5%), Conclusion: No clinically significant impairment of myocardial systolic function, as measured by LV GLS, was detected in this predominantly Caucasian male population of PWHIV on long-term ART, with no history of cardiovascular disease.

Indexed as

cardiovascular diseaseechocardiogramglobal longitudinal strainHIVleft ventricular systolic function

Identifiers

PMID37547256
PMCPMC10399116

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